Duarte galactosemia (DG or D/G galactosemia) - Diseases and Conditions Identified in Children

Duarte galactosemia (DG or D/G galactosemia)


Duarte galactosemia (DG or D/G galactosemia) is an inborn error of metabolism, an inherited condition in which an enzyme, galactose-1-phosphate uridyltransferase (GALT), in the body is not working well as well as usual. The job of this enzyme is to break down a sugar (called galactose). When this enzyme isn’t working as well as usual galactose might build up in the body. Galactose is found in milk and all foods that contain milk, some other types of foods and even some medications. Galactose is also made by a person’s own body. Duarte galactosemia typically does not result in the same health complications as classic galactosemia or other types of galactosemia. A person with Duarte galactosemia has more enzyme working in their body than a person with classic galactosemia. Babies with Duarte galactosemia often have no symptoms. Some children with Duarte galactosemia manage the condition with a special diet; if they are treated with a special diet, children are often only on the diet for the first year of life. More information about the health of individuals with Duarte galactosemia is needed to better understand long-term health outcomes.

A listing of contact information for Minnesota inborn errors of metabolism medical specialty providers/clinics serving children affected with or undergoing evaluation for conditions that can be detected through Minnesota Newborn Screening is available upon request.