Fatty Acid Oxidation Disorders - Diseases and Conditions Identified in Children

Fatty Acid Oxidation Disorders

Fatty acid oxidation disorders are a group of rare, inherited metabolic conditions. These health conditions prevent the body from converting certain fats to use for energy, and too many fatty acids can build-up in the body. The cause of each fatty acid oxidation disorder is different, and signs or symptoms and treatments vary. Support is available for families of children and youth with fatty acid oxidation disorders.

Condition-specific information and resources are available in English and Spanish on the Baby's First Test website:

Carnitine acylcarnitine translocase deficiency (CACT)

Carnitine palmitoyltransferase type I deficiency (CPT-1A)

Carnitine palmitoyltransferase type II deficiency II (CPT-II)

Carnitine uptake defect (CUD)

2,4 Dienoyl-CoA reductase deficiency (De-Red)

Glutaric acidemia type II (GA-2)

Long-chain L-3 hydroxyacyl-CoA dehydrogenase deficiency (LCHAD)

Medium-chain acyl-CoA dehydrogenase deficiency (MCAD)

Medium/short-chain L-3 hydroxyacyl-CoA dehydrogenase deficiency (SCHAD)

Medium-chain ketoacyl-CoA thiolase deficiency (MCKAT)

Short-chain acyl-CoA dehydrogenase deficiency (SCAD)

Trifunctional protein deficiency (TFP)

Very long-chain acyl-CoA dehydrogenase deficiency (VLCAD)

Family Stories: newborn screening family stories on the Minnesota Department of Health website, including stories about fatty acid oxidation conditions.

MinneStories: a project to record and preserve the stories of Minnesota families with conditions that can be identified by newborn screening. These stories of impact are shared so we may understand more about how newborn screening affects the lives of people all around us. MinneStories includes family stories about fatty acid oxidation condition(s).