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Glutaric Acidemia, Type II (GA2)


Glutaric acidemia, type II (GA2) is an inborn error of metabolism, an inherited condition in which the body is unable to break down certain fats and proteins well. This causes harmful substances to build up in the body. Signs and symptoms can vary and may include poor feeding, vomiting, breathing problems, extreme tiredness/lethargy, muscle weakness, low blood sugar (hypoglycemia), “sweaty feet” odor, heart problems, liver problems and/or other potential signs and symptoms. GA2 can be a life-threatening condition. Illnesses or infections, going too long without food, or eating large amounts of protein are some examples of circumstances that could also trigger symptoms of GA2. Management often includes a special diet, medication/supplements, other special precautions and emergency management recommendations. Support groups are available to help connect families living with GA2 with others who have experience or expertise with this condition.

To learn more about Glutaric acidemia, type II, visit Screening, Technology, and Research in Genetics (STAR-G): Glutaric acidemia, type 2 and Baby's First Test: Glutaric acidemia, type 2. Please see Medically Prescribed Formula for information about medically prescribed formula and pharmacologic interventions for inborn errors of metabolism. A listing of contact information for Minnesota inborn errors of metabolism medical specialty providers/clinics serving children affected with or undergoing evaluation for conditions that can be detected through Minnesota Newborn Screening is available upon request.