Glutaric Acidemia, Type II (GA-2)

 

Glutaric acidemia, type II (GA-2) is a condition in which the body is unable to break down certain fats and proteins. It is considered a fatty acid oxidation condition because people with GA-2 are unable to convert some of the fats and proteins they eat into energy the body needs to function. This causes too many unused fatty acids and other harmful substances to build up in the body. GA-2 can cause weak muscle tone, severe heart problems, and death. For some individuals with GA-2, detecting it early and beginning treatment may help to prevent some of the severe health outcomes associated with the condition.

This condition is also known as: glutaric acidemia type II, electron transfer flavoprotein deficiency, EMA ETFA deficiency, ETFDH deficiency, ethylmalonic-adipicaciduria, MAD, MADD, multiple acyl-CoA dehydrogenase deficiency, and multiple FAD dehydrogenase deficiency.

To learn more about Glutaric acidemia, type II, visit Screening, Technology, and Research in Genetics (STAR-G): Glutaric acidemia, type 2 and Baby's First Test: Glutaric acidemia, type 2. Please see Medically Prescribed Formula for information about medically prescribed formula and pharmacologic interventions for inborn errors of metabolism. Visit Board Certified Metabolic Providers for a listing of medical specialists and clinic contact information.