Hypermethioninemia (MET) - Diseases and Conditions Identified in Children

Hypermethioninemia (MET)


Hypermethioninemia (MET) is an inborn error of metabolism, an inherited condition in which an enzyme, methionine-S-adenosyltransferase (MAT I/III), in the body is either missing or not working well. Hypermethioninemia is an amino acid condition. When this enzyme is not working properly the body is unable to break down an amino acid called methionine (a part of protein). Reportedly, people with hypermethioninemia due to this genetic cause often do not show signs of the condition. However, some people with this condition have been reported to have health effects such as neurologic concerns.

For more information about Hypermethioninemia, visit Baby's First Test: Hypermethioninemia. A listing of contact information for Minnesota inborn errors of metabolism medical specialty providers/clinics serving children affected with or undergoing evaluation for conditions that can be detected through Minnesota Newborn Screening is available upon request.