Isobutyrylglycinuria (IBG)

 

Isobutyrylglycinuria (IBG) is an inherited condition in which the body is unable to break down certain proteins. It is an organic acid condition because IBG can lead to a harmful amount of organic acids and other toxins in the body. Symptoms of IBG vary. If IBG is identified early and treatment is begun, individuals with this condition may be able to lead healthy lives.

This condition is also known as: IBD deficiency, isobutyryl-CoA dehydrogenase deficiency, isobutyryl-coenzyme A dehydrogenase deficiency, acyl-CoA dehydrogenase family - member 8, ACAD8 deficiency.

To learn more about Isobutyrylglycinuria, visit Baby's First Test: Isobutyrylglycinuria and Screening, Technology, and Research in Genetics (STAR-G): Isobutyryl-CoA dehydrogenase deficiency. Please see Medically Prescribed Formula for information about medically prescribed formula and pharmacologic interventions for inborn errors of metabolism.