Organic Acid - Diseases and Conditions Identified in Children

Organic Acid Disorders

Organic acid disorders are a group of rare, inherited metabolic conditions. Each specific organic acid condition has a different cause, and signs or symptoms and treatments vary. Support is available for families of children and youth with organic acid disorders.

Condition-specific information and resources are available in English and Spanish on the Baby's First Test website:

2-methyl 3-hydroxybutyric acidemia (2M3HBA)

2-methylbutyrylglycinuria (2MBG)

3-hydroxy 3-methylglutaric aciduria (HMG)

3-methylcrotonyl-CoA carboxylase deficiency (3-MCC)

3-methylglutaconic aciduria (3MGA) - 3-methylglutaconyl-CoA hydratase deficiency

Beta-ketothiolase deficiency (BKT)

Glutaric acidemia type I (GA-1)

Holocarboxylase synthetase deficiency (also known as early-onset multiple carboxylase deficiency)

Isobutyrylglycinuria (IBG)

Isovaleric acidemia (IVA)

Malonic acidemia (MAL)

Methylmalonic acidemia (Methylmalonyl-CoA mutase deficiency)

Methylmalonic acidemia (Cobalamin disorders)

Methylmalonic acidemia with homocystinuria

Propionic acidemia (PROP)

MinneStories: a project to record and preserve the stories of Minnesota families with conditions that can be identified by newborn screening. These stories of impact are shared so we may understand more about how newborn screening affects the lives of people all around us. MinneStories includes family stories about organic acid condition(s).