Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD)

 

Short-chain acyl-CoA dehydrogenase deficiency (SCAD) is a condition in which the body is unable to break down certain fats. SCAD is considered a fatty acid oxidation condition because people affected by the condition are unable to change some of the fats they eat into energy the body needs to function. Most individuals who are identified as having SCAD never experience symptoms, while some individuals experience serious health effects. Detecting the condition early and beginning treatment may help prevent many of the serious outcomes of SCAD.

This condition is also known as: SCADD deficiency, ACADS deficiency, lipid-storage myopathy secondary to short-chain acyl-CoA dehydrogenase deficiency, SCADH deficiency, short-chain acyl-coenzyme A dehydrogenase deficiency.

To learn more about Short-chain acyl-CoA dehydrogenase deficiency, visit Screening, Technology, and Research in Genetics (STAR-G): Short-chain acyl-CoA dehydrogenase deficiency and Baby's First Test: Short-chain acyl-CoA dehydrogenase deficiency. Please see Medically Prescribed Formula for information about medically prescribed formula and pharmacologic interventions for inborn errors of metabolism. Visit Board Certified Metabolic Providers (PDF: 2 pages/204KB) for a listing of medical specialists and clinic contact information.