Toxicological Studies for PFBA

At the request of the Minnesota Department of Health (MDH) 3M funded a short-term (28 day exposure) study and a subchronic (90 day exposure) study to evaluate the toxicity of perfluorobutanoic acid (PFBA) in laboratory animals. These two studies are made available here in response to a request made at the legislature's PFC Oversight meeting on December 14, 2007.  These studies will be considered together with other sources of toxicological information as MDH determines a health based value for PFBA.

28-Day Oral Exposure Study in Rats

Complete Report (PDF: 14,002KB/359 pages)
Main Text (PDF: 1,761KB/27 pages)
Appendix 1 (PDF: 1,232KB/37 pages)
Appendix 2 (PDF: 3,944KB/100 pages)
Appendix 3 (PDF: 343KB/9 pages)
Appendix 4 (PDF: 6,748KB/186 pages)

90-Day Oral Exposure Study in Rats

Complete Report (PDF: 12,845KB/346 pages)
Main Text (PDF: 1,827KB/30 pages)
Appendix 1 (PDF: 1,114KB/42 pages)
Appendix 2 (PDF: 3,035KB/80 pages)
Appendix 3 (PDF: 237KB/7 pages)
Appendix 4 (PDF: 4,937KB/155 pages)
Appendix 5, 6, 7 (PDF: 1,472KB/32 pages)

More information on health based guidance for contaminants in water

For more information on health guidelines:
Perfluorooctanoic Acid (PFOA)
Perfluorooctane Sulfonate (PFOS)

Updated Wednesday, 17-Jul-2013 14:25:30 CDT