Pneumococcal Vaccination Pocket Guide
A guide to assist healthcare providers in determing who should receive a pneumococcal vaccination.
Download PDF version formatted for print:
Pneumococcal Vaccination Pocket Guide (PDF: 46KB/2 pages)
On this page:
Indications
Contraindications and precautions
Unknown history
Vaccine administration
Who gets a second dose of PPSV
Talking points with patients
Indications
Pneumococcal polysaccharide vaccine (PPSV) is indicated for persons age 65 years or older, or age 2 through 64 years with any of the following:
- Chronic cardiovascular disease (e.g., CHF, cardiomyopathies)
- Chronic pulmonary disease (e.g., emphysema or COPD, including asthma)
- Cigarette smokers age 19 through 64 years
- Chronic liver disease, including persons with long-term alcoholism
- Diabetes mellitus
- CSF leaks
- Functional or anatomic asplenia (e.g., sickle cell disease or splenectomy)
- Immunosuppressive conditions (e.g., HIV infection, leukemia, congenital immunodeficiency, Hodgkin’s disease, lymphoma, multiple myeloma, or generalized malignancy)
- Organ or bone marrow transplantation
- Therapy with alkylating agents, antimetabolites, or systemic corticosteroids
- Chronic renal failure or nephrotic syndrome
- Cochlear implants
Contraindications and precautions
- Previous anaphylactic reaction to PPSV or any of its components
- Moderate to severe illness
Unknown history
Make a reasonable effort to obtain a vaccination history. When in doubt, vaccinate. The risks of invasive pneumococcal disease outweigh the risks of revaccination.
Vaccine administration
Administer 0.5 ml PPSV intramuscularly (IM) or subcutaneously (SC):
- IM: 1 - 1.5” 22-25 gauge needle OR
- SC: 5/8” 23-25 gauge needle
- Children age 2 years or older at risk for invasive pneumococcal disease need PPSV. It should be separated by 8 weeks from a dose of PCV.
Who gets a second dose of PPSV

A maximum of two PPSV doses in a lifetime is all that is recommended.
|
|
| Age of patient: | Spacing between shots: |
Age 2 through 9 years |
3 years apart |
| Age 10 through 64 years | At least 5 years apart |
| Age 65 years or older | At least 5 years apart |
Talking points with patients
- Most pneumococcal deaths are in people age 65 or older.
- Flu and its most common complication, pneumonia, are the sixth leading cause of death in Minnesota.
- PPSV is 60-70% effective in preventing most strains of pneumonia from spreading to the blood (bacteremia) or brain (meningitis). Immunization can prevent prolonged hospitalization or death due to invasive pneumococcal disease.
- The vaccine is important because pneumococcal disease is increasingly drug-resistant and hard to treat.
- Medicare Part B and most health plans pay for the vaccine.
- The vaccine is safe; the most common side effect is a sore arm lasting 24-48 hours.
- PPSV can be given at any time during the year.
- It’s okay to get this shot at the same time as the flu shot or any other vaccine.

