Powassan (POW) Virus Information for Health Professionals

Powassan (POW) virus is a tick-transmitted flavivirus.

On this page:
Clinical Presentation/Diagnosis
Reporting

Powassan disease

Powassan virus (POWV), a tick-borne flavivirus related to West Nile virus, can cause encephalitis or meningitis. Six cases have been identified in Minnesota residents from 2008-2010. One strain of POWV is transmitted by I. scapularis ticks (which also carry Lyme disease).

  • Serum or CSF specimens from patients with central nervous system disease can be submitted directly to the MDH Public Health Laboratory for arboviral disease testing, including POWV. At this time, no commercial laboratories offer serologic testing for POWV.

June 29, 2011: Tick-borne Disease Health Alert
Minnesota Records First Death from Tick-Borne Powassan Virus

Full May 6, 2011: Tick-borne Disease Health Alert

 

Clinical Presentation/Diagnosis

  • Medical providers should consider POW virus infection in patients with encephalitis or meningitis of probable unknown etiology that occurs during the tick-borne disease transmission season (May to October).
  • Signs and symptoms of POW encephalitis or meningitis may include fever, headache, vomiting, weakness, confusion, loss of coordination, speech difficulties, and memory loss.
  • Long-term sequelae are common, and the case-fatality rate in reported cases is approximately 10%.

Reporting

  • Reporting Powassan Virus
    Minnesota Rules Governing Communicable Diseases require health care providers to report confirmed or suspected cases of Powassan to the Minnesota Department of Health (MDH) within 1 working day.

MDH staff also are available to provide clinical consultation regarding diagnosis and treatment of Powassan and other tick-borne diseases. Call 651-201-5414 for a clinical consultation.

Updated Wednesday, 29-Jun-2011 13:16:12 CDT