Tuberculosis Medications Program
The Minnesota Department of Health (MDH) Tuberculosis (TB) Prevention and Control Program provides TB medications free of charge for persons with latent TB infection (LTBI) or active TB disease who reside in Minnesota. Treatment regimens using medications supplied by MDH must follow the Centers for Disease Control and Prevention/American Thoracic Society/Infectious Diseases Society of America guidelines for treatment of LTBI or treatment of active TB disease. Attention: Non-MDH web link
| TB Drug Shortage - January 15, 2013 Supply of INH during the national shortage. |
On this page:
Medications for latent TB infection
Medication for active TB disease
Medication for latent TB infection
To request medications for the treatment of LTBI, the provider should
contact the MDH TB Medications Coordinator at 651-201-5414 or 1-877-676-5414.
The provider will be asked to provide pertinent demographic and clinical
information and a copy of the prescription(s).
The completed LTBI Medication Request Form (PDF:75KB/2 pages) (fill-in version Word:108KB/2 pages) may be faxed to 651-201-5500 or mailed to:
| TB Medications Coordinator MDH TB Prevention and Control Program Minnesota Department of Health P.O. Box 64975 St. Paul, MN 55164-0975 |
Please note that all requests for the 12-Week INH-RPT Regimen must be accompanied by a completed Individual Plan for Using the Isoniazid and Rifapentine (INH-RPT) Regimen (PDF: 27KB/1 page).
MDH (through its contracted pharmacy) will ship the patient's first month supply of LTBI medication to the designated clinic or local public health agency (or other provider licensed to administer medications) within 5 working days of when the request form is received. If the form is incomplete or the request is not consistent with national LTBI treatment guidelines (PDF:351KB/71 pages), the shipment may be delayed. Attention: Non-MDH web link
After treatment starts, complete and return the LTBI Medication Start Date Verification Form (PDF:56KB/1 page) that was included with the first shipment to fax number 651-201-5500 or mail to the above address. Upon receiving this verification, MDH will ship monthly refills until treatment is complete. If treatment is discontinued for any reason or patient is lost to follow-up, please contact MDH ASAP to stop shipments.
The health care professional who receives the medication shipments is responsible for monitoring the patient for adverse reactions and for adherence to the regimen. The timing and type of monitoring activities should be done according to CDC guidelines for each regimen. An updated LTBI: Monitoring Flow Sheet (PDF:105KB/2 pages) that includes the new isoniazid-rifapentine (INH-RPT) regimen is available from MDH to assist with this process.
- LTBI Dosing: INH (PDF:35KB/1 page)
Quick-reference dosing table for LTBI medication.
- Treatment of Latent Tuberculosis Infection: Maximizing Adherence (PDF:47KB/2 pages)
Fact sheet from the Centers for Disease Control and Prevention (CDC) that presents practical techniques for increasing patient adherence to LTBI treatment. Please contact MDH staff for additional guidance. Attention: Non-MDH link
- Interjurisdictional Tuberculosis Notification Form (PDF:69KB/1 page)
Designed by the National TB Controllers Association to standardize the transfer of TB clients. Please consult with MDH TB staff before completing this form. Attention: Non-MDH link
Medication for active TB disease
To request medications for treatment of active TB disease, the provider should contact the MDH TB Nurse Case Manager at 651-201-5414 or 1-877-676-5414. The provider will be asked to provide pertinent clinical and demographic information and a copy of the prescription(s).
Medications will be sent monthly to the designated clinic, local public health agency, or other provider licensed to administer medications.
If a patient being treated for active TB disease stops therapy,
fails to pick up medications, or if treatment is discontinued,
please contact the MDH TB Nurse Case Manager immediately.

