Tuberculosis Medications Program

The Minnesota Department of Health (MDH) Tuberculosis (TB) Prevention and Control Program provides TB medications free of charge for persons with latent TB infection (LTBI) or active TB disease who reside in Minnesota. Treatment regimens using medications supplied by MDH must follow the Centers for Disease Control and Prevention/American Thoracic Society/Infectious Diseases Society of America guidelines for treatment of LTBI or treatment of active TB disease. Attention: Non-MDH web link

On this page:
Medications for latent TB infection
Medication for active TB disease

Medication for latent TB infection

To request medications for the treatment of LTBI, the provider should contact the MDH TB Medications Coordinator at 651-201-5414 or 1-877-676-5414.

The provider will be asked to provide pertinent demographic and clinical information and a copy of the prescription(s).

The completed LTBI Medication Request Form (PDF:75KB/2 pages) (fill-in version Word:108KB/2 pages) may be faxed to 651-201-5500 or mailed to:

TB Medications Coordinator
MDH TB Prevention and Control Program
Minnesota Department of Health
P.O. Box 64975
St. Paul, MN 55164-0975


Please note that all requests for the 12-Week INH-RPT Regimen must be accompanied by a completed Individual Plan for Using the Isoniazid and Rifapentine (INH-RPT) Regimen (PDF: 27KB/1 page).

MDH (through its contracted pharmacy) will ship the patient's first month supply of LTBI medication to the designated clinic or local public health agency (or other provider licensed to administer medications) within 5 working days of when the request form is received. If the form is incomplete or the request is not consistent with national LTBI treatment guidelines (PDF:351KB/71 pages), the shipment may be delayed. Attention: Non-MDH web link

After treatment starts, complete and return the LTBI Medication Start Date Verification Form (PDF:56KB/1 page) that was included with the first shipment to fax number 651-201-5500 or mail to the above address. Upon receiving this verification, MDH will ship monthly refills until treatment is complete. If treatment is discontinued for any reason or patient is lost to follow-up, please contact MDH ASAP to stop shipments.

The health care professional who receives the medication shipments is responsible for monitoring the patient for adverse reactions and for adherence to the regimen. The timing and type of monitoring activities should be done according to CDC guidelines for each regimen. An updated LTBI: Monitoring Flow Sheet (PDF:105KB/2 pages) that includes the new isoniazid-rifapentine (INH-RPT) regimen is available from MDH to assist with this process.

Medication for active TB disease

To request medications for treatment of active TB disease, the provider should contact the MDH TB Nurse Case Manager at 651-201-5414 or 1-877-676-5414. The provider will be asked to provide pertinent clinical and demographic information and a copy of the prescription(s).

Medications will be sent monthly to the designated clinic, local public health agency, or other provider licensed to administer medications.

If a patient being treated for active TB disease stops therapy, fails to pick up medications, or if treatment is discontinued, please contact the MDH TB Nurse Case Manager immediately.

Updated Wednesday, 27-Nov-2013 08:22:04 CST