Haemophilus influenzae Invasive Disease, 2010

Eighty-one cases of invasive Haemophilus influenzae disease (1.5 per 100,000 population) were reported in 2010. Cases ranged in age from newborn to 97 years (median, 72 years). Forty-one (51%) cases had pneumonia, 32 (40%) had bacteremia without another focus of infection, 5 (6%) had meningitis, 1 (1%) had epiglottitis, 1 (1%) had cellulitis, and 1 (1%) had pyelonephritis. Eleven (14%) deaths were reported among these cases.

Of 78 H. influenzae isolates for which typing was performed at MDH, 8 (10%) were type f, 6 (8%) type a, 6 (8%) type e, 1 (1%) type b, and 57 (73%) were untypeable.

One case of type b (Hib) disease occurred in 2010, compared to 2 cases in 2009, 5 cases in 2008, and 1 case in 2007. The Hib case was identified in an adult >60 years of age. The case presented with pneumonia and survived.

The 11 deaths occurred in patients ranging in age from 21 year to 94 years. Five cases presented with bacteremia without another focus of infection, 5 cases presented with pneumonia, and 1 case presented with pyelonephritis. Ten cases had H. influenzae isolated from blood and 1 case had H. influenzae isolated from the kidney. Of the 10 cases with data available, all 10 had significant underlying medical conditions. Of the 11 cases who died, 7 case-isolates were untypeable, 1 was serotype a, and 3 were not available for serotyping.

Updated Monday, November 28, 2011 at 02:10PM