The Clinical Guide to Services is a comprehensive reference guide of testing services, shipping information and submission requirements. Efforts have been made to be concise and current with all information, but as testing procedures and regulations change, some information may not be current. Many of these tests are only available with prior approval from MDH. It is impossible to address all situations in this guide, so please contact us with any questions.

List of Tests (Alphabetical by Agent)

A | B | C | D | E | F| G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | XYZ


List of Tests by Agent

M

Malaria

See: Plasmodium spp.

Marriage License Serology

See: Treponema pallidum

Measles Virus - Detection in Clinical Samples

Methodology: Culture
Restrictions: None
Fee Sticker: Required
Specimen: Urine (>1 ml) in a sterile container
Throat swab in viral transport medium
Nasal swab in viral transport medium
Shipping: Ship within 24 hours at refrigeration temperature.
Turnaround: 21 days

This disease must be reported to MDH as required by State Rule 4605.7040

Measles Virus - IgM and IgG Antibody Detection

Methodology: Indirect fluorescent antibody and Enzyme Immunoassay
Tests Included in Panel: Measles Virus IgM, IgG; Rubella Virus IgM, Total
Restrictions:Contact Infectious Disease Epidemiology Prevention and Control at (651) 201-5414 or (877) 676-5414 before requesting this test.
Fee Sticker: Required
Specimen: Congenital or acute phase serum or paired sera
Shipping: Ship at refrigeration temperature.
Turnaround: Within 2 working days of specimen receipt

This disease must be reported to MDH as required by State Rule 4605.7040

Meningitis, Bacterial - Antigen Detection Panel

Methodology: Latex agglutination
Tests Included in Panel: Detection of Haemophilus influenzae type b, Streptococcus pneumoniae, Escherichia coli K1, Group B Streptococcus and Neisseria meningitidis Groups A, B, C, Y and W135
Tests may be requested individually.
Restrictions: None
Fee Sticker: Required
Specimen: CSF (0.5 ml)
Serum (1 ml)
Urine (10 ml) Urine is not recommended for detection of Group B Streptococcus antigen.
Actively growing pure culture on suitable medium
Shipping: Ship CSF, serum, urine frozen or refrigerated.
Ship cultures at room temperature.
Turnaround: Within 1 working day of specimen receipt

This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040

Meningitis, Bacterial - PCR Panel

Methodology: PCR
Tests Included in Panel: Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae
Tests may be performed individually.
Restrictions: Contact Infectious Disease Epidemiology Prevention and Control at (651) 201-5414 or (877) 676-5414 before requesting this test.
Fee Sticker: Not required
Specimen: CSF (0.5 ml)
Serum (0.5 ml)
Whole EDTA blood (0.5 ml)
Shipping: Ship at refrigeration temperature.
Turnaround: Not available
Comment: This test is for research use only.
This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040

Meningitis, Viral

See: Enterovirus

Meningococcemia

See: Neisseria meningitidis

Meningococcus

See: Neisseria meningitidis

Meningoencephalitis, Viral

See: Arbovirus, Enterovirus, other individual agents as indicated

Metapneumovirus, human

Methodology: PCR
Restrictions: Contact Infectious Disease Epidemiology Prevention and Control at (651) 201-5414 or (877) 676-5414 before requesting this test.
Fee Sticker: Not required
Specimen: Nasopharyngeal swab, dry or in viral transport medium
Throat swab, dry or in viral transport medium
Nasal wash (0.5 ml)
Bronchoalveolar lavage, pleural fluid, tracheal aspirate (0.5 ml)
Shipping: Ship at refrigeration temperature.
Comment: This test is for research use only.

Methicillin Resistant Staphylococcus aureus (MRSA)

See: Staphylococcus aureus, Methicillin Resistant

Microfilariae

See: Filarial nematodes

Microsporidia (Encephalitozoon spp.) - Detection of DNA in Clinical Samples

Methodology: PCR
Restrictions: Contact laboratory at (651) 201-5048 before requesting this test
Fee Sticker: Not required
Specimen: Stool, fresh
Stool sample in non-formalin preservative or transport medium (e.g. PVA, EcoFix Cary-Blair)
Shipping: Unpreserved stool or stool in Cary-Blair: ship at refrigeration temperature
Stool in preservative: ship at room or refrigeration temperature.
Turnaround: Not available
Comments: This test is for research use only. Test differentiates Encephalitozoon intestinalis, E. hellum, and E. cuniculi.

Monkeypox virus - Detection in Clinical Samples

See also: Rash Illness Panel
Methodology: Culture
Restrictions: Contact Infectious Disease Epidemiology Prevention and Control at (651) 201-5414 or (877) 676-5414 before requesting this test.
Fee Sticker: Not required
Specimen: Roof of lesion in a sterile container
Swab of lesion in viral transport medium
Touch-prep (slide) of vesicular fluid
Biopsy material
Shipping: Ship at refrigeration temperature. Turnaround: 21 days

Monkeypox virus - Detection of DNA in Clinical Samples

Methodology: PCR (Laboratory Response Network protocols)
Restrictions: Contact Infectious Disease Epidemiology Prevention and Control at (651) 201-5414 or (877) 676-5414 before requesting this test.
Fee Sticker: Not required
Specimen: Roof of lesion in a sterile container
Swab of lesion, dry or in transport medium. Contact lab for details.
Touch-prep (slide) of vesicular fluid
Shipping: Contact laboratory for transport instructions.
Turnaround: Not available
Comments: This test is for research use only.

MRSA (Methicillin Resistant Staphylococcus aureus)

See: Staphylococcus aureus, Methicillin-Resistant

Mumps Virus - Detection in Clinical Samples

Methodology: Culture
Restrictions:Contact Infectious Disease Epidemiology Prevention and Control at (651) 201-5414 or (877) 676-5414 before requesting this test.
Fee Sticker: Required
Specimen: Throat swab in viral transport medium
Urine (>1 ml) in a sterile container
CSF (>1 ml)
Shipping: Ship at refrigeration temperature.
Turnaround: 14 days

This disease must be reported to MDH as required by State Rule 4605.7040

Mumps Virus - IgG Antibody Detection

Methodology: Enzyme Immunoassay
Restrictions:Contact Infectious Disease Epidemiology Prevention and Control at (651) 201-5414 or (877) 676-5414 before requesting this test.
Fee Sticker: Required
Specimen: Congenital or acute phase serum or paired sera
Shipping: Ship at refrigeration temperature.
Turnaround: Sent to CDC; no turnaround time available.

This disease must be reported to MDH as required by State Rule 4605.7040

Mycobacterium avium Complex

See: Mycobacterium spp. (not tuberculosis)

Mycobacterium bovis and bovis BCG - Identification/Confirmation of Referred Isolate

Methodology: Varies
Restrictions: None
Fee Sticker: Not Required
Specimen: Actively growing culture on suitable solid medium
Growth in BACTEC bottle
Growth in MGIT tube
Shipping: Ship at room temperature, sealed culture system.
Turnaround: Not available
Comments: M. bovis and M. bovis BCG are members of the M. tuberculosis complex. Speciation may be requested if there has been consumption of unpasteurized dairy products (M. bovis) or complications of BCG therapy for bladder cancer or vaccine. Sent to CDC for speciation.

Mycobacterium spp. - Identification/Confirmation of Referred Isolate

Methodology: Nucleic acid probe, HPLC, conventional biochemicals
Restrictions: None
Fee Sticker: Not required
Specimen: Actively growing pure culture on suitable solid medium
Growth in BACTEC bottle
Growth in MGIT tube
Shipping: Ship at room temperature, sealed culture system.
Turnaround: Probe results available within 3 working days. Biochemical identification varies.

Mycobacterium spp. (not tuberculosis) - Antimicrobial Susceptibility Testing

Restrictions: Testing is done on request only and must be billed directly to the submitter.
Fee Sticker: Not required
Specimen: Actively growing pure culture on suitable solid medium
Growth in BACTEC bottle
Growth in MGIT tube
Shipping: Ship at room temperature, sealed culture system.
Turnaround: Varies
Comments: Isolates are sent to National Jewish Mycobacterial Reference Lab, Denver, CO.

Mycobacterium spp. (not tuberculosis) - Detection in Clinical Samples

Methodology: Concentrated acid-fast smear, Culture
Restrictions: None
Fee Sticker: Required
Specimen: See Specimen Requirements
Shipping: Ship blood and bone marrow at room temperature, other specimens at refrigeration temperature.
Turnaround: Smear available within 1 working day. Negative culture results available after 6 weeks of incubation.

Mycobacterium tuberculosis Complex - Antimicrobial Susceptibility Testing, First-Line Drugs

Methodology: Performed by MGIT 960 method
Drugs Included in Panel: isoniazid, rifampin, ethambutol and pyrazinamide
Restrictions: Done automatically on initial patient isolate and subsequent isolates with evidence of treatment failure.
Fee Sticker: Not required
Specimen: Actively growing pure culture on suitable solid medium
Growth in BACTEC bottle
Growth in MGIT tube
Shipping: Ship at room temperature, sealed culture system.
Turnaround: Usually within 14 days of receipt or isolation of organism.

This disease must be reported to MDH as required by State Rule 4605.7040

Mycobacterium tuberculosis Complex - Antimicrobial Susceptibility Testing, Second-line Drugs

Restrictions: Done automatically on isolates resistant to 2 or more first-line drugs, or resistant to rifampin only.
Fee Sticker: Not required
Specimen: Actively growing pure culture on suitable solid medium
Growth in BACTEC bottle
Growth in MGIT tube
Shipping: Ship at room temperature, sealed culture system.
Turnaround: Varies
Comments: Sent to CDC for testing.

This disease must be reported to MDH as required by State Rule 4605.7040

Mycobacterium tuberculosis Complex - Detection in Clinical Samples

Methodology: Concentrated acid-fast smear, Culture
Restrictions: None
Fee Sticker: Required
Specimen: See Specimen Requirements
Shipping: Ship at refrigeration temperature.
Turnaround: Smear available within 1 working day. Negative culture results available after 6 weeks of incubation.

This disease must be reported to MDH as required by State Rule 4605.7040

Mycobacterium tuberculosis Complex - Identification/Confirmation of Referred Isolate

Methodology: Nucleic acid probe, HPLC, and conventional biochemicals
Restrictions: None
Fee Sticker: Not required
Specimen: Actively growing pure culture on suitable solid medium
Growth in BACTEC bottle
Growth in MGIT tube
Shipping: Ship at room temperature, sealed culture system.
Turnaround: Probe results available within 3 working days. Biochemical identification varies.

This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040

Mycobacterium tuberculosis Complex - Molecular Subtyping

Methodology: Restriction fragment length polymorphism
Restrictions: Done at the request of epidemiology staff only.
Fee Sticker: Not required
Specimen: Actively growing pure culture on suitable solid medium
Growth in BACTEC bottle
Growth in MGIT tube
Shipping: Ship at room temperature, sealed culture system.
Turnaround: Not available
Comments: Sent to regional genotyping laboratory

This disease must be reported to MDH as required by State Rule 4605.7040

Mycoplasma pneumoniae - Detection of DNA in Clinical Samples

Methodology: PCR
Restrictions: Contact Infectious Disease Epidemiology Prevention and Control at (651) 201-5414 or (877) 676-5414 before requesting this test
Fee Sticker: Not required
Specimen: Nasopharyngeal or throat swab, dry or in transport medium
Sputum (0.5 ml)
Bronchoalveolar lavage, pleural fluid, tracheal aspirate (0.5 ml)
Shipping: Ship at refrigeration temperature.
Turnaround: Not available
Comments: This test is for research use only.


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Updated Wednesday, 20-Apr-2011 10:17:53 CDT