Medical Cannabis Clinical Information Resources
The publications below are resources for learning more about the cannabis plant and the endocannabinoid system, medical uses of cannabis preparations, and potential benefits and harms of medical cannabis use. Most of these have references that can be used to guide further inquiry into more specific aspects of each topic, research evidence involving medical cannabis for specific diseases, and more detailed evidence regarding potential harms. Please get in touch with the Office of Medical Cannabis to suggest additional resources for the Office to consider posting here.
- Monitoring Health Concerns Related to Marijuana in Colorado: 2014
Colorado Department of Public Health and Environment. Changes in marijuana use patterns, systematic literature review, and possible marijuana-related health effects.
- Information for Health Care Professionals: Cannabis and the cannabinoids (PDF)
Health Canada. February, 2013. Endocannabinoid system, clinical pharmacology, dosing, potential therapeutic uses (by condition), precautions, warnings, adverse effects, and overdose/toxicity.
- Handbook of Cannabis
Roger G Pertwee, Oxford University Press, 2014. 747 pages.
- Constituents, History, International Control, Cultivation, and Phenotypes of Cannabis
- Pharmacology, Pharmacokinetics, Metabolism, and Forensics
- Medical Cannabis and Cannabinoids: Clinical Data
- Approved Therapeutic Targets for Phytocannabinoids: Preclinical Pharmacology
- Some Potential Therapeutic Targets for Phytocannabinoids
- Recreational Cannabis: Sought-After Effects, Adverse Effects, Designer Drugs, and Harm Minimization
- A Review of Medical Cannabis Studies relating to Chemical Compositions and Dosages for Qualifying Medical Conditions (PDF)
Office of Medical Cannabis. Summary of clinical trials and prospective observational studies in humans, published in peer-reviewed journals, which focus on medical cannabis formulations consistent with Minnesota’s medical cannabis program.
- Brief Review of Studies Regarding Increased Risk of Harm with Cannabis Use (PDF)
This document presents a brief review of cannabis studies relevant to three groups of persons at increased risk of harm with cannabis use: Children, adolescents, and young adults; Women who are pregnant or breastfeeding; and persons with a personal or family history of psychotic disorder such as schizophrenia.
- The pharmacologic and clinical effects of medical cannabis
Pharmacotherapy 2013;33(2):195-209. Borgelt LM, Franson KL, Nussbaum AM, Wang GS.
Pharmacodynamics and pharmacokinetics (smoked and orally ingested) of cannabis, clinical effects (focusing on pain and muscle spasm), adverse effects and drug interactions, psychiatric implications, and pediatric implications.
- Medical marijuana for cancer
CA Cancer J Clin. 2015 Mar;65(2):109-22. doi: 10.3322/caac.21260. Epub 2014 Dec 10. Kramer JL.
Potential medical uses for marijuana and cannabinoids in cancer, based on systematic literature review. Includes good short sections on cannabinoid receptors and cannabinoids and pharmaceutical forms of cannabinoids.
- Cannabis for symptom control #279
J Palliat Med. 2014 May;17(5):612-4. doi: 10.1089/jpm.2014.9431. Epub 2014 Apr 21. Aggarwal SK, Blinderman CD.
A very short, but good, review of pharmacology, dosing, side effects/risks, and evidence of effectiveness for conditions relevant to palliative care.
- Adverse effects of medical cannabinoids: a systematic review
CMAJ. 2008;178:1669-1678. Wang T, Collet J, Shapiro S, Ware MA.
Literature review and assessment based on 31 medical cannabis studies that met inclusion and exclusion criteria.