Carbapenem Resistant Pseudomonas aeruginosa (CRPA) Information for Health Professionals:
CRPA Sentinel Surveillance Case Definition and Reporting
Starting July 1, 2016 Carbapenemase Resistant Pseudomonas aeruginosa (CRPA) is reportable for residents of Hennepin and Ramsey Counties under Minnesota Rules 4605.7000 to 4605.7900.
On this page:
What to report (in Hennepin and Ramsey Counties)
How to report
Isolate submission and laboratory testing
Reporting rule change: proposal and notification letters
What to report (in Hennepin and Ramsey Counties)
- Pseudomonas aeruginosa isolated from any body site, that meets the following criteria:
- Resistant to imipenem, meropenem, or doripenem based on current Clinical and Laboratory Standards Institutes Standards (CLSI) M100 standards; and/or
- Demonstrates production of a carbapenemase by a recognized method (e.g. CarbaNP or PCR).
- Current CLSI minimum inhibitory concentration (MIC) interpretive criteria for carbapenem-resistant Pseudomonas aeruginosa (CRPA):
| Antibiotic | MIC (µg/mL) |
| Imipenem | ≥ 8 |
| Meropenem | ≥ 8 |
| Doripenem | ≥ 8 |
References
- Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fourth Informational Supplement (January 2016). CLSI document M100-S24. Wayne, Pennsylvania, 2016.
How to report
- Yellow Disease Report Card
CPRA may be reported using the MDH "Yellow Card."
- Phone
Any reportable infectious disease may be reported by phone to 651-201-5414 or 877-676-5414.
Isolate submission and laboratory testing
- CRPA Isolate Submission and Laboratory Testing
Laboratory testing protocols for CRPA and isolate submission to MDH.
