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  1. Home
  2. Diseases and Conditions
  3. C. difficile (Clostridioides difficile, Clostridium difficile)
  4. Health Professional Information on Clostridioides (Clostridium) difficile
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Health Professionals C. diff Information

  • C. diff Health Professionals Home
  • Clinical Information
  • Testing and Treatment
  • Disease Reporting
  • Infection Prevention
  • Changing Epidemiology
  • Guidelines and Resources

Related Topics

  • C. difficile Home
  • Infection Prevention & Control
  • Antimicrobial Resistance and Stewardship
  • Healthcare-Associated Infections
  • Hand Hygiene

Health Professionals C. diff Information

  • C. diff Health Professionals Home
  • Clinical Information
  • Testing and Treatment
  • Disease Reporting
  • Infection Prevention
  • Changing Epidemiology
  • Guidelines and Resources

Related Topics

  • C. difficile Home
  • Infection Prevention & Control
  • Antimicrobial Resistance and Stewardship
  • Healthcare-Associated Infections
  • Hand Hygiene
Contact Info
Infectious Disease Epidemiology, Prevention and Control Division
651-201-5414
IDEPC Comment Form

Contact Info

Infectious Disease Epidemiology, Prevention and Control Division
651-201-5414
IDEPC Comment Form

Clostridioides (Clostridium) difficile Guidelines and Resources

  • IDSA: Five Things Physicians and Patients Should Question
    A list from the Infectious Diseases Society of America (IDSA) of inappropriate and overused clinical practices related to antibiotic prescribing and C. difficile.
     
  • CDC: Clostridium difficile: Guidelines and Prevention Resources
    CDC C. difficile guidelines.
     
  • APIC: Guide to Preventing Clostridium difficile Infections (PDF)
    APIC Elimination Guide. Large file advisory- file may take some time to download.
     
  • JSTOR: Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by SHEA/IDSA
    2010 SHEA/IDSA recommendations regarding epidemiology, diagnosis, treatment, and infection control and environmental management for C. difficile.
     
  • Pediatrics: Clostridium difficile Infection in Infants and Children: Policy Statement
    For CDI testing and treatment recommendations for infants and children refer to the American Academy of Pediatrics policy statement.
     
  • ADA: Antibiotic Prophylaxis in Dentistry
    American Dental Association recommendations for use of antibiotics before dental treatment for patients with certain heart conditions and those with joint replacements.
     
  • EPA: Registered Antimicrobial Products Effective against Clostridium difficile Spores
    EPA Listing of disinfectant products with sporicidal activity against C. difficile.

For Acute Care

  • Strategies to prevent Clostridium difficile infections in acute care hospitals
    2008 SHEA/IDSA Compendium of infection prevention recommendations for acute care hospitals.
     
  • Safe from Clostridioides (Clostridium) difficile infection (CDI) Toolkit/Roadmap
    This two-tiered intervention approach (core and enhanced) includes four topic areas: early recognition of patients with CDI, isolation precautions, environmental cleaning and disinfection, and antimicrobial stewardship.

For Long Term Care

  • Algorithms for Prevention and Management of Clostridioides (Clostridium) difficile Infections in Long-term Care Facilities (PDF)
    MDH guidance for Clostridioides (Clostridium) difficile prevention and control including: early recognition and testing, Contact Precautions, room placement, identifying roommates, environmental cleaning and disinfection, and social and activity precautions.

Resources

  • Burden of Clostridium difficile Infection in the United States
    N Engl J Med. 2015 Feb 26; 372(9): 825-834.
  • Death due to community-associated Clostridium difficile in a woman receiving prolonged antibiotic therapy for suspected Lyme disease
    Clin Infect Dis. August 1, 2010;51(1):369-70.
  • Epidemiology of community-associated Clostridium difficile infection, 2009 through 2011
    JAMA Intern Med. 2013 Jul; 173(14): 1359-67.
  • Effect of nucleic acid amplification testing on population-based incidence rates of Clostridium difficile infection
    Clin Infect Dis. 2013 November; 57(9):1304-1307.
  • Impact of changes in Clostridium difficile testing practices on stool rejection policies and C. difficile positivity rates across multiple laboratories in the United States
    J Clin Microbiol. 2014 Feb; 52(2): 632-4.
  • Clostridium difficile infection among children across diverse U.S. geographic locations
    Pediatrics. 2014 April; 133(4): 1-8. A.
  • NAP1 strain type predicts outcomes from Clostridium difficile infection
    Clin Infect Dis. 2014 May 15; 58(10): 1394-1400.
  • Determinants of Clostridium difficile infections across diverse U.S. geographic locations
    Open Forum Infect Dis (Summer 2014) 1 (2): doi:10.1093/ofid/ofu047.
  • Current Status of Clostridium difficile Infection Epidemiology
    Clin Infect Dis. 2012 Aug 1; 55(Suppl 2): S65-S70.

 

Tags
  • cdiff
Last Updated: 02/03/2023

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