Toxic Shock Syndrome, 2014: DCN - Minnesota Dept. of Health

Toxic Shock Syndrome (TSS), 2014

In 2014, 13 cases of suspect, probable, or confirmed staphylococcal toxic shock syndrome (TSS) were reported. Eight cases were female; the median age was 15 years (range, 9 to 72 years). Five cases were associated with tampon use. Two cases were associated with pneumonia, 1 of which was also menstrual associated. Three cases were fatal.

Staphylococcal toxic shock syndrome is reportable within 1 working day and includes submission of clinical isolates. The 2011 CDC case definition is used to classify cases. This definition encompasses the following clinical and laboratory findings: fever (temperature ≥102.0°F or 38.9°C), rash (diffuse macular erythroderma), desquamation (within 1-2 weeks after onset of illness), hypotension (SBP ≤ 90 mm Hg for adults or less than fifth percentile by age for children aged <16 years), multisystem involvement (>3 of the following: vomiting or diarrhea at onset of illness; severe myalgia or creatinine phosphokinase level at least twice the upper limit of normal; vaginal, oropharyngeal, or conjunctival hyperemia; blood urea nitrogen or creatinine at least twice the upper limit of normal for laboratory or urinary sediment with pyuria (>5 leukocytes per high-power field) in the absence of urinary tract infection; total bilirubin, alanine aminotransferase enzyme, or aspartate aminotransferase enzyme levels at least twice the upper limit of normal for laboratory; platelets less than 100,000/mm3; disorientation or alterations in consciousness without focal neurologic signs when fever and hypotension are absent); negative results for blood or cerebrospinal fluid cultures (blood culture may be positive for Staphylococcus aureus) or negative serologies for Rocky Mountain spotted fever, leptospirosis, or measles (if done).

Updated Tuesday, 28-May-2019 08:11:46 CDT