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Tests for Agents Beginning with “M”
The Clinical Guide to Services, from Minnesota’s Infectious Disease Laboratory
The Clinical Guide to Services is a comprehensive reference guide of testing services, shipping information, and submission requirements for Minnesota’s Infectious Disease Laboratory.
Even though there are ongoing efforts to keep information current, some information may not be up to date due to recent changes in testing procedures and/or regulation. Many of these tests are only available with prior approval from the Minnesota Department of Health.
If you cannot find what you are looking for in the guide, please Contact the Infectious Disease Laboratory.
Alphabetical by Agent
A | B | C | D | E | F | G | H | IJK | L | M | N |
O | P | Q | R | S | T | U | V | W | XYZ
| Test Name | Malaria |
| See: Plasmodium spp. | |
| Test Name | Marburg Virus |
| See: BioFire NGDS Warrior Panel | |
| Test Name | Measles Virus - Detection in Clinical Samples |
| Methodology | Culture |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | Confirmation of isolates only. This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Actively growing measles isolate on cell culture. |
| Shipping | Ship at room temperature. |
| Turnaround | 21 days |
| Test Name | Measles Virus - Detection in Clinical Samples |
| Methodology | RT-PCR |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Throat swab (preferred up to 9 days post onset), Urine (if 5 or more days post onset), Buccal swab, Nasal swab, Nasopharyngeal swab, Nasal wash, Nasopharyngeal wash, CSF if suspected meningitis or encephalitis, Isolate. Respiratory sources: Viral transport media, VTM, UTM, M5, M4, Saline, PBS, Liquid Stuarts; Urine and CSF in sterile container. 3 mL preferred/140 uL minimum. See: Lab Testing for Measles at the MDH PHL |
| Shipping | Store and ship at refrigerated temperature within 7 days of collection. Alternatively, ship frozen within 1 year of collection. |
| Turnaround | 1-3 days |
| Test Name | Measles Virus - Serology |
| Methodology | Capture IgM Enzyme Linked Immunosorbent Assay (ELISA) and Indirect IgG ELISA |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | Sent to CDC. Performed as Measles Serology CDC-10244. This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Collect blood in a red-top or serum-separator tube (SST). Tubes containing whole blood should not be stored frozen (-20°C or lower). Centrifuge blood collection tubes (10 minutes at 1000 – 1300 g) to separate serum from clot. Gel separation tubes should be centrifuged no more than 2 hours after collection. Aseptically transfer serum to a sterile tube that has an externally threaded cap with an o–ring seal. Refrigerate serum (2-8°C) within 8 hours of collection. Serum samples should not be stored at room temperature (15-25°C) for longer than 8 hours after collection. If the samples will be stored for more than 48 hours, freeze specimens (-20°C or lower). |
| Shipping | Ship at storage temperature. |
| Turnaround | 7 days after receipt at CDC |
| Test Name | Meningitis, Bacterial - PCR Panel |
| Methodology | PCR Tests Included in Panel: Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae Tests may be performed individually. |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040. |
| Specimen | CSF (0.5 ml) and isolates are preferred Whole EDTA blood (0.5 ml) |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | Not available |
| Test Name | Meningitis, Viral |
| See: Enterovirus | |
| Test Name | Meningococcemia |
| See: Neisseria meningitidis | |
| Test Name | Meningococcus |
| See: Neisseria meningitidis | |
| Test Name | Meningoencephalitis, Viral |
| See: Arbovirus Panel, Enterovirus, other individual agents as indicated. | |
| Test Name | Metapneumovirus, human |
| Methodology | PCR |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This test is for research use only. |
| Specimen | Nasopharyngeal swab, dry or in viral transport medium Throat swab, dry or in viral transport medium Nasal wash (0.5 ml) Bronchoalveolar lavage, pleural fluid, tracheal aspirate (0.5 ml) |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | Not available |
| Test Name | Methicillin Resistant Staphylococcus aureus (MRSA) |
| See: Staphylococcus aureus, Methicillin Resistant | |
| Test Name | Microfilariae |
| See: Filarial nematodes | |
| Test Name | Microsporidia (Encephalitozoon spp.) - Detection of DNA in Clinical Samples |
| Methodology | PCR |
| Pre-Approval | Contact laboratory at 651-201-5048 before requesting this test |
| Supplemental Information | This test is for research use only. Test differentiates Encephalitozoon intestinalis, E. hellum, and E. cuniculi |
| Specimen | Stool, fresh Stool sample in non-formalin preservative or transport medium (e.g. PVA, EcoFix Cary-Blair) |
| Shipping | Unpreserved stool or stool in Cary-Blair: ship at refrigeration temperature Stool in preservative: ship at room or refrigeration temperature. |
| Turnaround | Not available |
| Test Name | Monkeypox virus - Detection of DNA in Clinical Samples |
| Methodology | PCR |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | Testing at IDL is for Non-variola Orthopoxvirus; confirmatory testing for specific Orthopoxvirus (i.e. monkeypox, vaccinia, etc) is performed at CDC. Order Choice: Non-Variola Orthopoxvirus PCR |
| Specimen |
|
| Shipping | Specimens must be shipped at refrigeration temperature and received within 7 days of collection. |
| Turnaround | 1-3 days for screening at MDH-PHL. CDC confirmation results for presumptive positives when available |
| Test Name | MRSA (Methicillin Resistant Staphylococcus aureus) |
| See: Staphylococcus aureus, Methicillin-Resistant | |
| Test Name | Mumps Virus - Detection in Clinical Samples |
| Methodology | Culture |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Buccal or throat swab in viral transport medium Urine (>1 ml) in a sterile container CSF (>1 ml) |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | 14 days |
| Test Name | Mumps Virus - Detection in Clinical Samples |
| Methodology | PCR |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Buccal preferred. Throat swab, urine is acceptable if 5 days or more after symptom onset. |
| Shipping | Ship within 24 hours at refrigeration temperature |
| Turnaround | 2 working days upon receipt of specimen |
| Test Name | Mumps Virus - IgG Antibody Detection |
| Methodology | Enzyme Immunoassay |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Congenital or acute phase serum or paired sera |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | Sent to CDC. No turnaround time available. |
| Test Name | Mycobacterium avium Complex |
| See: Mycobacterium spp. (not tuberculosis) | |
| Test Name | Mycobacterium bovis and bovis BCG - Identification/Confirmation of Referred Isolate |
| Methodology | Varies - Sent to CDC |
| Pre-Approval | None |
| Supplemental Information | M. bovis and M. bovis BCG are members of the M. tuberculosis complex. Speciation may be requested if there has been consumption of unpasteurized dairy products ( M. bovis ) or complications of BCG therapy for bladder cancer or vaccine. Sent to CDC for speciation. |
| Specimen | Actively growing culture on suitable solid medium Growth in MGIT tube |
| Shipping | Ship at room temperature, sealed culture system. |
| Turnaround | Not available |
| Test Name | Mycobacterium spp. - Identification/Confirmation of Referred Isolate |
| Methodology | Line probe assay, Nucleic acid probe, conventional biochemicals |
| Pre-Approval | None |
| Supplemental Information | Fee $66 - $68 per sample |
| Specimen | Actively growing pure culture on suitable solid medium Growth in MGIT tube |
| Shipping | Ship at room temperature, sealed culture system. |
| Turnaround | Line probe and DNA probe results available within 3 working days. Biochemical identification varies. |
| Test Name | Mycobacterium spp. (not tuberculosis) - Antimicrobial Susceptibility Testing |
| Methodology | |
| Pre-Approval | |
| Supplemental Information | Isolates must be requested from MDH Mycobacteria Lab at 651-201-5053. Isolate will be sent back to submitting lab. |
| Specimen | |
| Shipping | |
| Turnaround | 48 Hours |
| Test Name | Mycobacterium spp. (not tuberculosis) - Detection in Clinical Samples |
| Methodology | Concentrated acid-fast smear, Culture |
| Pre-Approval | None |
| Supplemental Information | Fee $66 - $68 per sample |
| Specimen | See Specimen Requirements for Acid Fast Bacilli (AFB) |
| Shipping | Ship blood and bone marrow at room temperature, other specimens at refrigeration temperature. |
| Turnaround | Smear available within 1 working day. Negative culture results available after 6 weeks of incubation. |
| Test Name | Mycobacterium tuberculosis Complex - Antimicrobial Susceptibility Testing, First-Line Drugs |
| Methodology | Performed by MGIT 960 method Drugs Included in Panel: isoniazid, rifampin, ethambutol and pyrazinamide Done automatically on initial patient isolate and subsequent isolates with evidence of treatment failure. |
| Pre-Approval | None |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Actively growing pure culture on suitable solid medium Growth in MGIT tube |
| Shipping | Ship at room temperature, sealed culture system. |
| Turnaround | Usually within 14 days of receipt or isolation of organism. |
| Test Name | Mycobacterium tuberculosis Complex - Antimicrobial Susceptibility Testing, Second-line Drugs |
| Methodology | Send to CDC |
| Pre-Approval | None |
| Supplemental Information | Sent automatically on isolates resistant to 2 or more first-line drugs, or resistant to rifampin only. This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Actively growing pure culture on suitable solid medium Growth in MGIT tube |
| Shipping | Ship at room temperature, sealed culture system. |
| Turnaround | Varies |
| Test Name | Mycobacterium tuberculosis Complex - Detection in Clinical Samples |
| Methodology | Concentrated acid-fast smear, Culture |
| Pre-Approval | None |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | See Specimen Requirements for Acid Fast Bacilli (AFB) |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | Smear available within 1 working day. Negative culture results available after 6 weeks of incubation. |
| Test Name | Mycobacterium tuberculosis Complex and Mycobacterium avium Complex - Direct Testing |
| Methodology | PCR |
| Pre-Approval | TB disease must be suspected. |
| Supplemental Information | AFB smear result must accompany request if submitting digested sample. AFB smear negative specimens will not receive MAC PCR results. |
| Specimen | Respiratory specimen or NALC digested/decontaminated respiratory specimen. |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | Within 1 working day. |
| Test Name | Mycobacterium tuberculosis Complex - Identification/Confirmation of Referred Isolate |
| Methodology | Line probe assay, Nucleic acid probe and conventional biochemicals |
| Pre-Approval | None |
| Supplemental Information | This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040. |
| Specimen | Actively growing pure culture on suitable solid medium Growth in MGIT tube |
| Shipping | Ship at room temperature, sealed culture system. |
| Turnaround | Line probe and DNA probe results available within 3 working days. |
| Test Name | Mycoplasma pneumoniae - Detection of DNA in Clinical Samples |
| Methodology | PCR |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This test is for research use only. |
| Specimen | Nasopharyngeal or throat swab, dry or in transport medium Sputum (0.5 ml) Bronchoalveolar lavage, pleural fluid, tracheal aspirate (0.5 ml) Bronch wash (0.5 ml) |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | Not available |