Contact Info
Infectious Disease Epidemiology, Prevention and Control Division
651-201-5414
Syphilis Information for Health Professionals
General information about prevention, screening, diagnosis, complications, treatment, and reporting.
Bicillin L-A (penicillin G benzathine) Shortage
There has been a recall of specific lots of Bicillin® L-A (Penicillin G Benzathine Injectable Suspension) and CDC anticipates a limited supply moving forward. More information can be found at Bicillin L-A® Recall and Anticipated Shortage (PDF) and CDC: Bicillin® L-A.
New Syphilis Tools App
Syphilis Tools is a new, free app that providers can use to interpret serologic tests, identify syphilis stages, determine treatment regimens, and monitor titers. Visit New Syphilis Tools App for more information.

Screening and Treating Syphilis
- Clinical diagnosis, interpreting tests, and screening and treatment guidelines

Reporting Syphilis
- Case definition and tools to report a case

Syphilis in Pregnancy and Congenital Syphilis
- Information for health professionals on working with pregnant people

Syphilis Training and Resources
- Training modules and additional resources for health care providers
Last Updated: 09/17/2026