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Contact Info
Public Health Laboratory
651-201-5200
health.mdhlab@state.mn.us

Contact Info

Public Health Laboratory
651-201-5200
health.mdhlab@state.mn.us

Tests for Agents Beginning with “C”

The Clinical Guide to Services, from Minnesota’s Infectious Disease Laboratory

The Clinical Guide to Services is a comprehensive reference guide of testing services, shipping information, and submission requirements for Minnesota’s Infectious Disease Laboratory.

Even though there are ongoing efforts to keep information current, some information may not be up to date due to recent changes in testing procedures and/or regulation. Many of these tests are only available with prior approval from the Minnesota Department of Health.

If you cannot find what you are looking for in the guide, please Contact the Infectious Disease Laboratory.

Alphabetical by Agent

A | B | C | D | E | F | G | H | IJK | L | M | N |
O | P | Q | R | S | T | U | V | W | XYZ


Test Name Calicivirus
  See: Norovirus spp.
Test Name California (La Crosse) encephalitis
  See: Arbovirus Panel
Test Name Campylobacter spp. - Antimicrobial Susceptibility Testing
  See: Antimicrobial Susceptibility Testing
Test Name Campylobacter spp. - Detection in Clinical Samples
Methodology Culture
Pre-Approval None
Supplemental Information This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040.
Included in routine Enteric Bacterial Culture
Specimen Stool in ParaPak C&S, Modified Carey-Blair or equivalent - fill to line (approximately 5 ml).
Shipping Ship preserved samples at room temperature.
Turnaround Negative results available within 2-4 working days. Positive results are phoned to submitter as soon as available
Test Name Campylobacter spp. - Identification/Confirmation of Referred Isolate
Methodology Biochemical testing, MALDI-TOF
Pre-Approval None
Supplemental Information This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040.
Specimen Actively growing pure culture on suitable medium or Wang's transport medium (available from MDH).
Shipping Ship at room temperature.
Turnaround Identification from pure culture available in 1-6 working days.
Test Name Campylobacter spp. - Molecular Subtyping
  See: Pulsed-Field Gel Electrophoresis or Whole Genome Sequencing
Test Name Candida spp. - Identification/Confirmation of Referred Isolate
Methodology Culture morphology, Biochemical testing
Pre-Approval None
Supplemental Information None
Specimen Actively growing pure culture on suitable medium
Shipping Ship at room temperature.
Turnaround Within 1 week of specimen receipt
Test Name Chagas Disease
  See: Trypanosoma cruzi
Test Name Chanchroid
  See: Haemophilus ducreyi
Test Name Chancre
  See: Treponema pallidum
Test Name Chicken Pox
  See: Varicella Zoster Virus
Test Name Chikungunya Virus - RNA Detection
Methodology Molecular method Trioplex RT-PCR (Zika, Dengue, Chikungunya)
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test
Supplemental Information Urine must be submitted with a paired serum specimen. Urine will only be tested for Zika by RT-PCR.
Record the onset date on the submission form.
This disease must be reported to MDH as required by State Rule 4605.7040
For other testing/interpretation guidelines see Laboratory Zika Virus Testing
Specimen Serum, preferred (1ml) (Trioplex RT-PCR)
Shipping Ship at frozen temperature.
Turnaround 7 days
Test Name Chlamydophila pneumoniae (Chlamydia pneumoniae) - Detection of DNA in Clinical Samples
Methodology PCR
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test
Supplemental Information This test is for research use only.
Specimen Nasopharyngeal or throat swab, dry or in transport medium
Sputum (0.5 ml)
Bronchoalveolar lavage, pleural fluid, tracheal aspirate (0.5 ml)
Shipping Ship at refrigeration temperature.
Turnaround Not available
Test Name Cholera
  See: Vibrio SPP.
Test Name Clostridium botulinum - Detection in Clinical and Environmental Samples and Food
Methodology Culture
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information This disease must be reported to MDH as required by State Rule 4605.7040.
This organism has been designated as a Select Agent (Select Agent Regulation, 42 CFR, 73, Final Rule). Special handling criteria apply. Please contact the laboratory for special instructions.
Specimen See: Collection and Transport of Samples for Botulism Testing
Shipping See: Collection and Transport of Samples for Botulism Testing
Turnaround Within 10 working days of specimen receipt
Test Name Clostridium botulinum - Identification/Confirmation of Referred Isolate
Methodology Biochemical, molecular and immunological testing using the Laboratory Resource Response Network
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information This disease must be reported to MDH as required by State Rule 4605.7040.
This organism has been designated as a Select Agent (Select Agent Regulation, 42 CFR, 73, Final Rule). Special handling criteria apply. Please contact the laboratory for special instructions.
Specimen Actively growing pure culture on suitable medium
Shipping Ship at room temperature.
Turnaround Within 5 working days of specimen receipt.
Test Name Clostridium botulinum toxin - Detection in Clinical and Environmental Samples and Food
Methodology Toxin Neutralization Assay and immunological methods using the Laboratory Resource Network protocols.
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information This disease must be reported to MDH as required by State Rule 4605.7040.
This organism has been designated as a Select Agent (Select Agent Regulation, 42 CFR, 73, Final Rule). Special handling criteria apply. Please contact the laboratory for special instructions.
Specimen See: Collection and Transport of Samples for Botulism Testing
Shipping See: Collection and Transport of Samples for Botulism Testing
Turnaround Within 5 working days of specimen receipt
Test Name Clostridium perfringens - Detection in Stool or Implicated Food
Methodology Culture
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information This disease must be reported to MDH as required by State Rule 4605.7040.
Done for investigation of foodborne illness only.
Specimen Stool in ParaPak C&S, Modified Carey-Blair or equivalent - fill to line (approximately 5 ml)
Implicated food - minimum of 10 g in original container or transferred to sterile container using sterile instruments.
Shipping Ship stool at room temperature, food at refrigeration temperature.
Turnaround Within 5 working days of specimen receipt
Test Name Clostridium perfringens - Detection of Enterotoxin Type A in Stool
Methodology Reversed passive latex agglutination
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information Done for investigation of foodborne illness only.
Specimen Stool in ParaPak C&S, Modified Carey-Blair or equivalent - fill to line (approximately 5 ml)
Shipping Ship at room temperature.
Turnaround Within 5 days of specimen receipt.
Test Name Clostridium perfringens - Identification/Confirmation of Referred Isolate
Methodology Biochemical testing, Toxin testing
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information Toxin testing is done for investigation of foodborne illness only.
Specimen Actively growing pure culture on suitable medium
Shipping Ship at room temperature.
Turnaround Within 5 working days of specimen receipt.
Test Name Clostridium tetani - Identification/Confirmation of Referred Isolate
Methodology Biochemical testing, Toxin testing
Pre-Approval None
Supplemental Information If required, toxin testing is performed at CDC.
This disease must be reported to MDH as required by State Rule 4605.7040.
Specimen Actively growing pure culture on suitable medium
Shipping Ship at room temperature.
Turnaround Within 2 weeks of specimen receipt
Test Name CMV
  See: Cytomegalovirus
Test Name Coccidioides immitis - Antibody Detection
  See: Fungal Serology
Test Name Coccidioides immitis - Identification/Confirmation of Referred Isolate
Methodology Culture morphology, Nucleic acid probe
Pre-Approval None
Supplemental Information None.
Specimen Actively growing pure culture on suitable medium
Shipping Ship at room temperature, sealed culture system.
Turnaround Probe results within 1 working day of specimen receipt
Test Name Corynebacterium diphtheriae - Detection in Clinical Samples
Methodology Culture
Pre-Approval Contact laboratory at 651-201-5073 and/or Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040.
Specimen Nasopharyngeal swab, throat swab, membrane sample
Inoculate Loeffler's slant (available from MDH), leave swab on slant. Deliver to laboratory immediately or incubate at 37C and deliver within 18 hours of inoculation.
Shipping Ship at room temperature.
Turnaround Negative results available after 48 hours of incubation
Test Name Corynebacterium diphtheriae - Identification/Confirmation of Referred Isolate
Methodology Microscopic morphology, Growth characteristics. Other methods as needed.
Pre-Approval Contact laboratory at 651-201-5073 and/or Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040.
Specimen Actively growing culture on suitable medium
Shipping Ship at room temperature.
Turnaround C. diphtheriae ruled out within 1 working day of specimen receipt
Test Name COVID -19 PCR (SARS-CoV-2) 
Methodology PCR
Pre-Approval None
Supplemental Information COVID-19 Guidance
Specimen Upper respiratory tract specimens: NP swab, OP swab, nasal swab, NP/OP swab in the same container, NP wash/aspirate, nasal aspirate.
Lower respiratory tract specimens: Sputum, bronchoalveolar lavage, and tracheal aspirates.
Shipping Ship at refrigeration temperature or frozen if greater than 72 hours old. Samples will be rejected if received at room temperature. If sample was frozen before sending, please document that on form.
Turnaround 0-3 days
Test Name Coxiella burnetii - Detection of DNA in Clinical Samples
Methodology Molecular testing using the Laboratory Response Network Protocols
Pre-Approval See current guidance for acceptable submissions.
Supplemental Information Results are only presumptive. Samples must be sent to the CDC for confirmation. This disease must be reported to MDH as required by State Rule 4605.7040.
This organism has been designated as a Select Agent (Select Agent Regulation, 42 CFR, 73, Final Rule). Special handling criteria apply. Please contact the laboratory for special instructions.
Specimen None.
Shipping Ship at refrigeration temperature.
Turnaround 2 days
Test Name Coxsackie virus
  See: Enterovirus
Test Name CRE - Carbapenemase Resistant Enterbacteriaceae
  See: Klebsiella spp. Carbapenemase-Producers (KPC)
Test Name Cryptococcus neoformans - Identification/Confirmation of Referred Isolate
Methodology Culture morphology, Biochemical testing
Pre-Approval None
Supplemental Information None
Specimen Actively growing pure culture on suitable medium
Shipping Ship at room temperature.
Turnaround Identification from pure culture available within 2 weeks
Test Name Cryptosporidium spp. (C. parvum, C. hominis) - Detection in Clinical Samples
Methodology Concentration, Acid-fast stain, and Direct fluorescent antibody
Pre-Approval None
Supplemental Information This disease must be reported to MDH as required by State Rule 4605.7040.
Specimen Stool preserved in both formalin and PVA (or equivalent) - fill to line (kits are available from MDH)
Prepared fecal concentrate
Stained or unstained permanent slides
Shipping Ship at room temperature.
Turnaround Within 3 working days of specimen receipt
Test Name Cryptosporidium spp. ( C. parvum, C. hominis ) - Identification/Confirmation of Referred Specimen
Methodology Microscopic Examination, Acid-fast stain, Direct fluorescent antibody
Pre-Approval None
Supplemental Information This disease must be reported to MDH as required by State Rule 4605.7040.
Specimen Prepared fecal concentrate
Stained or unstained permanent slides
Shipping Ship at room temperature.
Turnaround Within 5 working days of specimen receipt
Test Name Cryptosporidium spp. (C. parvum, C. hominis ) - Molecular Subtyping
Methodology PCR, restriction fragment length polymorphism analysis, DNA sequencing
Pre-Approval Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test.
Supplemental Information This disease must be reported to MDH as required by State Rule 4605.7040.
This test is for research use only.
Specimen Stool, fresh
Stool sample in preservative (non-formalin preferred) or transport medium (e.g. PVA, EcoFix Cary-Blair)
Shipping Unpreserved stool: ship at refrigeration temperature
Stool in preservative: ship at room or refrigeration temperature.
Turnaround Unavailable
Test Name Cutaneous larva migrans (Anyclostoma spp.) - Antibody Detection
  See: Parasite Serology
Test Name Cyclospora cayetanensis - Detection in Clinical Samples
Methodology Concentration, Acid-fast stain, and Autofluorescence
Pre-Approval None
Supplemental Information None
Specimen Stool preserved in both formalin and PVA (or equivalent) - fill to line (kits are available from MDH)
Prepared fecal concentrate
Stained or unstained permanent slides
Shipping Ship at room temperature.
Turnaround Within 3 working days of specimen receipt
Test Name Cyclospora cayetanensis - Identification/Confirmation of Referred Specimen
Methodology Microscopic Examination, Acid-fast stain, Autofluorescence
Pre-Approval None
Supplemental Information None
Specimen Prepared fecal concentrate
Stained or unstained permanent slides
Shipping Ship at room temperature.
Turnaround Within 3 working days of specimen receipt.
Test Name Cysticercosis (Larval Taenia solium ) - Antibody Detection
  See: Parasite Serology
Test Name Cytomegalovirus - Detection in Clinical Samples
Methodology Culture
Pre-Approval None
Supplemental Information None
Specimen Urine (>1 ml)
Throat swab in viral transport medium
Lung sample in viral transport medium
Shipping Ship at refrigeration temperature.
Turnaround Within 21 days of specimen receipt
Tags
  • infectious disease lab
Last Updated: 11/23/2022

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