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Tests for Agents Beginning with “C”
The Clinical Guide to Services, from Minnesota’s Infectious Disease Laboratory
The Clinical Guide to Services is a comprehensive reference guide of testing services, shipping information, and submission requirements for Minnesota’s Infectious Disease Laboratory.
Even though there are ongoing efforts to keep information current, some information may not be up to date due to recent changes in testing procedures and/or regulation. Many of these tests are only available with prior approval from the Minnesota Department of Health.
If you cannot find what you are looking for in the guide, please Contact the Infectious Disease Laboratory.
Alphabetical by Agent
A | B | C | D | E | F | G | H | IJK | L | M | N |
O | P | Q | R | S | T | U | V | W | XYZ
| Test Name | Calicivirus |
| See: Norovirus spp. | |
| Test Name | California (La Crosse) encephalitis |
| See: Arbovirus Panel | |
| Test Name | Campylobacter spp. - Antimicrobial Susceptibility Testing |
| See: Antimicrobial Susceptibility Testing | |
| Test Name | Campylobacter spp. - Detection in Clinical Samples |
| Methodology | Culture |
| Pre-Approval | None |
| Supplemental Information | This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040. Included in routine Enteric Bacterial Culture |
| Specimen | Stool in ParaPak C&S, Modified Carey-Blair or equivalent - fill to line (approximately 5 ml). |
| Shipping | Ship preserved samples at room temperature. |
| Turnaround | Negative results available within 2-4 working days. Positive results are phoned to submitter as soon as available |
| Test Name | Campylobacter spp. - Identification/Confirmation of Referred Isolate |
| Methodology | Biochemical testing, MALDI-TOF |
| Pre-Approval | None |
| Supplemental Information | This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040. |
| Specimen | Actively growing pure culture on suitable medium or Wang's transport medium (available from MDH). |
| Shipping | Ship at room temperature. |
| Turnaround | Identification from pure culture available in 1-6 working days. |
| Test Name | Campylobacter spp. - Molecular Subtyping |
| See: Pulsed-Field Gel Electrophoresis or Whole Genome Sequencing | |
| Test Name | Candida spp. - Identification/Confirmation of Referred Isolate |
| Methodology | Culture morphology, Biochemical testing |
| Pre-Approval | None |
| Supplemental Information | None |
| Specimen | Actively growing pure culture on suitable medium |
| Shipping | Ship at room temperature. |
| Turnaround | Within 1 week of specimen receipt |
| Test Name | Chagas Disease |
| See: Trypanosoma cruzi | |
| Test Name | Chanchroid |
| See: Haemophilus ducreyi | |
| Test Name | Chancre |
| See: Treponema pallidum | |
| Test Name | Chicken Pox |
| See: Varicella Zoster Virus | |
| Test Name | Chikungunya Virus - RNA Detection |
| Methodology | Molecular method Trioplex RT-PCR (Zika, Dengue, Chikungunya) |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test |
| Supplemental Information | Urine must be submitted with a paired serum specimen. Urine will only be tested for Zika by RT-PCR. Record the onset date on the submission form. This disease must be reported to MDH as required by State Rule 4605.7040 For other testing/interpretation guidelines see Laboratory Zika Virus Testing |
| Specimen | Serum, preferred (1ml) (Trioplex RT-PCR) |
| Shipping | Ship at frozen temperature. |
| Turnaround | 7 days |
| Test Name | Chlamydophila pneumoniae (Chlamydia pneumoniae) - Detection of DNA in Clinical Samples |
| Methodology | PCR |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test |
| Supplemental Information | This test is for research use only. |
| Specimen | Nasopharyngeal or throat swab, dry or in transport medium Sputum (0.5 ml) Bronchoalveolar lavage, pleural fluid, tracheal aspirate (0.5 ml) |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | Not available |
| Test Name | Cholera |
| See: Vibrio SPP. | |
| Test Name | Clostridium botulinum - Detection in Clinical and Environmental Samples and Food |
| Methodology | Culture |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. This organism has been designated as a Select Agent (Select Agent Regulation, 42 CFR, 73, Final Rule). Special handling criteria apply. Please contact the laboratory for special instructions. |
| Specimen | See: Collection and Transport of Samples for Botulism Testing |
| Shipping | See: Collection and Transport of Samples for Botulism Testing |
| Turnaround | Within 10 working days of specimen receipt |
| Test Name | Clostridium botulinum - Identification/Confirmation of Referred Isolate |
| Methodology | Biochemical, molecular and immunological testing using the Laboratory Resource Response Network |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. This organism has been designated as a Select Agent (Select Agent Regulation, 42 CFR, 73, Final Rule). Special handling criteria apply. Please contact the laboratory for special instructions. |
| Specimen | Actively growing pure culture on suitable medium |
| Shipping | Ship at room temperature. |
| Turnaround | Within 5 working days of specimen receipt. |
| Test Name | Clostridium botulinum toxin - Detection in Clinical and Environmental Samples and Food |
| Methodology | Toxin Neutralization Assay and immunological methods using the Laboratory Resource Network protocols. |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. This organism has been designated as a Select Agent (Select Agent Regulation, 42 CFR, 73, Final Rule). Special handling criteria apply. Please contact the laboratory for special instructions. |
| Specimen | See: Collection and Transport of Samples for Botulism Testing |
| Shipping | See: Collection and Transport of Samples for Botulism Testing |
| Turnaround | Within 5 working days of specimen receipt |
| Test Name | Clostridium perfringens - Detection in Stool or Implicated Food |
| Methodology | Culture |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. Done for investigation of foodborne illness only. |
| Specimen | Stool in ParaPak C&S, Modified Carey-Blair or equivalent - fill to line (approximately 5 ml) Implicated food - minimum of 10 g in original container or transferred to sterile container using sterile instruments. |
| Shipping | Ship stool at room temperature, food at refrigeration temperature. |
| Turnaround | Within 5 working days of specimen receipt |
| Test Name | Clostridium perfringens - Detection of Enterotoxin Type A in Stool |
| Methodology | Reversed passive latex agglutination |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | Done for investigation of foodborne illness only. |
| Specimen | Stool in ParaPak C&S, Modified Carey-Blair or equivalent - fill to line (approximately 5 ml) |
| Shipping | Ship at room temperature. |
| Turnaround | Within 5 days of specimen receipt. |
| Test Name | Clostridium perfringens - Identification/Confirmation of Referred Isolate |
| Methodology | Biochemical testing, Toxin testing |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | Toxin testing is done for investigation of foodborne illness only. |
| Specimen | Actively growing pure culture on suitable medium |
| Shipping | Ship at room temperature. |
| Turnaround | Within 5 working days of specimen receipt. |
| Test Name | Clostridium tetani - Identification/Confirmation of Referred Isolate |
| Methodology | Biochemical testing, Toxin testing |
| Pre-Approval | None |
| Supplemental Information | If required, toxin testing is performed at CDC. This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Actively growing pure culture on suitable medium |
| Shipping | Ship at room temperature. |
| Turnaround | Within 2 weeks of specimen receipt |
| Test Name | CMV |
| See: Cytomegalovirus | |
| Test Name | Coccidioides immitis - Antibody Detection |
| See: Fungal Serology | |
| Test Name | Coccidioides immitis - Identification/Confirmation of Referred Isolate |
| Methodology | Culture morphology, Nucleic acid probe |
| Pre-Approval | None |
| Supplemental Information | None. |
| Specimen | Actively growing pure culture on suitable medium |
| Shipping | Ship at room temperature, sealed culture system. |
| Turnaround | Probe results within 1 working day of specimen receipt |
| Test Name | Corynebacterium diphtheriae - Detection in Clinical Samples |
| Methodology | Culture |
| Pre-Approval | Contact laboratory at 651-201-5073 and/or Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040. |
| Specimen | Nasopharyngeal swab, throat swab, membrane sample Inoculate Loeffler's slant (available from MDH), leave swab on slant. Deliver to laboratory immediately or incubate at 37C and deliver within 18 hours of inoculation. |
| Shipping | Ship at room temperature. |
| Turnaround | Negative results available after 48 hours of incubation |
| Test Name | Corynebacterium diphtheriae - Identification/Confirmation of Referred Isolate |
| Methodology | Microscopic morphology, Growth characteristics. Other methods as needed. |
| Pre-Approval | Contact laboratory at 651-201-5073 and/or Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease is reportable. Isolates must be submitted to MDH as required by State Rule 4605.7040. |
| Specimen | Actively growing culture on suitable medium |
| Shipping | Ship at room temperature. |
| Turnaround | C. diphtheriae ruled out within 1 working day of specimen receipt |
| Test Name | COVID -19 PCR (SARS-CoV-2) |
| Methodology | PCR |
| Pre-Approval | None |
| Supplemental Information | COVID-19 Guidance |
| Specimen | Upper respiratory tract specimens: NP swab, OP swab, nasal swab, NP/OP swab in the same container, NP wash/aspirate, nasal aspirate. Lower respiratory tract specimens: Sputum, bronchoalveolar lavage, and tracheal aspirates. |
| Shipping | Ship at refrigeration temperature or frozen if greater than 72 hours old. Samples will be rejected if received at room temperature. If sample was frozen before sending, please document that on form. |
| Turnaround | 0-3 days |
| Test Name | Coxiella burnetii - Detection of DNA in Clinical Samples |
| Methodology | Molecular testing using the Laboratory Response Network Protocols |
| Pre-Approval | See current guidance for acceptable submissions. |
| Supplemental Information | Results are only presumptive. Samples must be sent to the CDC for confirmation. This disease must be reported to MDH as required by State Rule 4605.7040. This organism has been designated as a Select Agent (Select Agent Regulation, 42 CFR, 73, Final Rule). Special handling criteria apply. Please contact the laboratory for special instructions. |
| Specimen | None. |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | 2 days |
| Test Name | Coxsackie virus |
| See: Enterovirus | |
| Test Name | CRE - Carbapenemase Resistant Enterbacteriaceae |
| See: Klebsiella spp. Carbapenemase-Producers (KPC) | |
| Test Name | Cryptococcus neoformans - Identification/Confirmation of Referred Isolate |
| Methodology | Culture morphology, Biochemical testing |
| Pre-Approval | None |
| Supplemental Information | None |
| Specimen | Actively growing pure culture on suitable medium |
| Shipping | Ship at room temperature. |
| Turnaround | Identification from pure culture available within 2 weeks |
| Test Name | Cryptosporidium spp. (C. parvum, C. hominis) - Detection in Clinical Samples |
| Methodology | Concentration, Acid-fast stain, and Direct fluorescent antibody |
| Pre-Approval | None |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Stool preserved in both formalin and PVA (or equivalent) - fill to line (kits are available from MDH) Prepared fecal concentrate Stained or unstained permanent slides |
| Shipping | Ship at room temperature. |
| Turnaround | Within 3 working days of specimen receipt |
| Test Name | Cryptosporidium spp. ( C. parvum, C. hominis ) - Identification/Confirmation of Referred Specimen |
| Methodology | Microscopic Examination, Acid-fast stain, Direct fluorescent antibody |
| Pre-Approval | None |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. |
| Specimen | Prepared fecal concentrate Stained or unstained permanent slides |
| Shipping | Ship at room temperature. |
| Turnaround | Within 5 working days of specimen receipt |
| Test Name | Cryptosporidium spp. (C. parvum, C. hominis ) - Molecular Subtyping |
| Methodology | PCR, restriction fragment length polymorphism analysis, DNA sequencing |
| Pre-Approval | Contact Infectious Disease Epidemiology Prevention and Control at 651-201-5414 or 877-676-5414 before requesting this test. |
| Supplemental Information | This disease must be reported to MDH as required by State Rule 4605.7040. This test is for research use only. |
| Specimen | Stool, fresh Stool sample in preservative (non-formalin preferred) or transport medium (e.g. PVA, EcoFix Cary-Blair) |
| Shipping | Unpreserved stool: ship at refrigeration temperature Stool in preservative: ship at room or refrigeration temperature. |
| Turnaround | Unavailable |
| Test Name | Cutaneous larva migrans (Anyclostoma spp.) - Antibody Detection |
| See: Parasite Serology | |
| Test Name | Cyclospora cayetanensis - Detection in Clinical Samples |
| Methodology | Concentration, Acid-fast stain, and Autofluorescence |
| Pre-Approval | None |
| Supplemental Information | None |
| Specimen | Stool preserved in both formalin and PVA (or equivalent) - fill to line (kits are available from MDH) Prepared fecal concentrate Stained or unstained permanent slides |
| Shipping | Ship at room temperature. |
| Turnaround | Within 3 working days of specimen receipt |
| Test Name | Cyclospora cayetanensis - Identification/Confirmation of Referred Specimen |
| Methodology | Microscopic Examination, Acid-fast stain, Autofluorescence |
| Pre-Approval | None |
| Supplemental Information | None |
| Specimen | Prepared fecal concentrate Stained or unstained permanent slides |
| Shipping | Ship at room temperature. |
| Turnaround | Within 3 working days of specimen receipt. |
| Test Name | Cysticercosis (Larval Taenia solium ) - Antibody Detection |
| See: Parasite Serology | |
| Test Name | Cytomegalovirus - Detection in Clinical Samples |
| Methodology | Culture |
| Pre-Approval | None |
| Supplemental Information | None |
| Specimen | Urine (>1 ml) Throat swab in viral transport medium Lung sample in viral transport medium |
| Shipping | Ship at refrigeration temperature. |
| Turnaround | Within 21 days of specimen receipt |