Pathogen Genomics Centers of Excellence
PGCoE Publications

Minnesota's Pathogen Genomics Centers of Excellence (PGCoE) projects have yielded several papers published in peer-reviewed academic journals:

• Minnesota Department of Health scientists, along with colleagues at the University of Minnesota and University of Pennsylvania, developed an interdisciplinary model to investigate how carbapenemase-producing Enterobacterales transmit across human and animal populations. The World Health Organization and Centers for Disease Control and Prevention (CDC) have cited carbapenemase-producing Enterobacterales as being among the most urgent antimicrobial resistance (AR) threats.
• The People, Pets and Plasmids project has produced a paper linking human and animal cases of infection by multi-drug-resistant organisms. The story was also covered by the University of Minnesota's Center for Infectious Disease Research and Policy: Two investigations reveal how resistant bacteria may have spread from pets to people.
• Minnesota Department of Health scientists used whole-genome sequencing to research recurring infections of Clostridioides difficile (C. diff).
• In investigating a recent increase in gonorrhea cases, Minnesota Department of Health scientists discovered that a rare strain of the bacteria responsible for the disease has become more prevalent.
• A collaboration between the Minnesota Department of Health and the Mayo Clinic has resulted in the discovery of a new organism relevant to public health.
• A team of molecular biologists and epidemiologists at the Minnesota Department of Health wrote a detailed analysis of respiratory syncytial virus (RSV) genomes.