Human Health-Based Water Guidance Table
The Minnesota Department of Health (MDH) develops health-based rules and guidance to evaluate potential human health risks from exposures to chemicals in groundwater. For more information, see: Guidance Values and Standards for Contaminants in Drinking Water or contact the Health Risk Assessment Unit.
Key to table entries
Value Type: HRL = Health Risk Limits; HBV = Health-Based Values; and RAA = Risk Assessment Advice. Subscripts either indicate the last two digits of the year the value was developed or that the HRL is based on a US EPA Maximum Contaminant Level (MCL).
Exposure Duration: Acute = one day exposure; Short-term = greater than one day up to 30 days; Subchronic = greater than 30 days up to 10% of a lifetime; Chronic = greater than 10% of a lifetime; and Cancer = zero to 70 years of age
Related links
Other Minnesota Guidance is also available for certain methods and substances, including lead, dioxins, PAHs, Total Petroleum Hydrocarbon (TPH), as well as rapid assessment values for pesticides and pharmaceuticals.
A Comparison of State Water Guidance and Federal Drinking Water Standards is also available.
When multiple substances are present MDH risk assessment methods require evaluation of the potential risk from the combined exposure. Information from the water guidance table below and a calculator for exposures to multiple chemicals is available for download:
MDH Water Guidance and Additivity Calculator (Excel).
Guidance Table
| CAS Number | Chemical | Value Type | Exposure Duration |
Value (µg/L) |
Health Endpoint(s) |
|---|---|---|---|---|---|
| Find chemicals beginning with: A - C D - E F - M N - S T - Z | |||||
| 83-32-9 | Acenaphthene |
HRL18 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 200 | Adrenal; Liver system | |||
| Chronic | 100 | Adrenal; Liver system | |||
| Cancer | NA | -- | |||
| 103-90-2 | Acetaminophen |
HRL15 | Acute | 200 | Liver system |
| Short-term | 200 | Liver system | |||
| Subchronic | 200* | Liver system | |||
| Chronic | 200* | Liver system | |||
| Cancer | NA | -- | |||
| 34256-82-1 |
Acetochlor Toxicological Summary for Acetochlor
(PDF) See also degradates: |
HRL18 | Acute | ND | -- |
| Short-term | 30 | Developmental; Liver system; Thyroid (E) | |||
| Subchronic | 30 | Liver system; Male reproductive system; Nervous system; Kidney system | |||
| Chronic | 20 | Liver system; Male reproductive system; Nervous system; Kidney system; Respiratory system | |||
| Cancer | NA | -- | |||
| 187022-11-3 |
Acetochlor ESA (degradate of Acetochlor) Toxicological Summary for Acetochlor ESA (PDF) Information Sheet: Acetochlor ESA and Drinking Water (PDF)
|
HRL18 | Acute | ND | -- |
| Short-term | 500 | Thyroid (E) | |||
| Subchronic | 500 | Male reproductive system; Thyroid (E) | |||
| Chronic | 300 | Male reproductive system; Thyroid (E) | |||
| Cancer | NA | -- | |||
| 184992-44-4 | Acetochlor OXA (degradate of Acetochlor) |
HRL18 | Acute | ND | -- |
| Short-term | 100 | Thyroid (E) | |||
| Subchronic | 100* | Thyroid (E) | |||
| Chronic | 90 | Thyroid (E) | |||
| Cancer | NA | -- | |||
| 67-64-1 | Acetone |
HRL11*** | Acute | ND | -- |
| Short-term | 9,000 | Kidney system | |||
| Subchronic | 8,000 | Kidney system; Blood system | |||
| Chronic | 4,000 | Kidney system; Blood system | |||
| Cancer | NA | -- | |||
Acetone |
HBV20 | Acute | ND | -- | |
| Short-term | 5,000 | Kidney system | |||
| Subchronic | 5,000* | Kidney system | |||
| Chronic | 3,000 | Blood system; Liver system; Kidney system | |||
| Cancer | NA | -- | |||
| 21145-77-7 or 1506-02-1 | 6-Acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN or Tonalide) Toxicological Summary for 6-Acetyl-1,12,4,4,7-hexamethyltetraline (PDF) |
HRL13 | Acute | ND | -- |
| Short-term | 100 | Liver system | |||
| Subchronic | 30 | Liver system | |||
| Chronic | 20 | Liver system | |||
| Cancer | NA | -- | |||
| 79-06-1 | Acrylamide |
HRL15 | Acute | ND | -- |
| Short-term | 7 | Developmental; Male reproductive system; Nervous system | |||
| Subchronic | 7* | Developmental; Male reproductive system; Nervous system | |||
| Chronic | 7* | Developmental; Male reproductive system; Nervous system | |||
| Cancer | 0.2 | Cancer | |||
| 15972-60-8 | Alachlor Toxicological Summary for Alachlor (PDF) See also degradates |
HRL18 | Acute | ND | -- |
| Short-term | 100 | Developmental; Kidney system | |||
| Subchronic | 60 | Blood system; Liver system; Kidney system | |||
| Chronic | 9 | Blood system; Liver system; Kidney system | |||
| Cancer | NA | -- | |||
| 142363-53-9 |
Toxicological Summary for Alachlor ESA (PDF) |
RAA16 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 100 | Blood system | |||
| Chronic | 50 | Blood system | |||
| Cancer | NA | -- | |||
| 171262-17-2 |
Toxicological Summary for Alachlor OXA (PDF) |
RAA16 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 100 | Blood system | |||
| Chronic | 50 | Blood system | |||
| Cancer | NA | -- | |||
| 116-06-3 | Aldicarb | HRL93 | Chronic | 1 | Nervous system |
| 107-05-1 | Allyl chloride (3 chloropropene) | HRL94 | Chronic | 30 | Nervous system |
| 1066-51-9 | Aminomethylphosphonic acid (AMPA) Toxicological Summary for Aminomethylphosphonic acid (PDF) Information Sheet: AMPA and Drinking Water (PDF)
|
HBV17 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 3000 | Liver system; renal system | |||
| Chronic | 1000 | Liver system; renal system | |||
| Cancer | NA | -- | |||
| 64285-06-9 | Anatoxin-a |
RAA16 | Acute | ND | -- |
| Short-term | 0.1 | Nervous system | |||
| Subchronic | ND | -- | |||
| Chronic | ND | -- | |||
| Cancer | ND | -- | |||
| 120-12-7 | Anthracene |
HRL93*** | Chronic | 2,000 | None |
| RAA19 | Acute | ND | -- | ||
| Short-term | ND | -- | |||
| Subchronic | 1,000 | NA | |||
| Chronic | 600 | NA | |||
| Cancer | NA | -- | |||
| 7440-36-0 | Antimony | HRL93 | Chronic | 6 | -- |
| 1912-24-9 | Atrazine See also degradates Deethylatrazine, Deethyldeisopropylatrazine, and Deisopropylatrazine as described in the Toxicological Summary for Cyanazine and Atrazine Chlorinated Degradates (PDF) |
HRLMCL | Chronic | 3 | see USEPA Organic Chemicals table |
| 7440-39-3 | Barium | HRL93 | Chronic | 2,000 | Cardiovascular system |
| 25057-89-0 | Bentazon |
HRL15 | Acute | 400 | Developmental; Female reproductive system |
| Short-term | 60 | Developmental | |||
| Subchronic | 50 | Blood system | |||
| Chronic | 30 | Thyroid | |||
| Cancer | NA | -- | |||
| 71-43-2 | Benzene |
HRL09 | Acute | 10 | Developmental |
| Short-term | 10 | Blood system; Immune system | |||
| Subchronic | 3 | Blood system; Immune system | |||
| Chronic | 3** | Blood system; Immune system | |||
| Cancer | 2 | Cancer | |||
| 50-32-8 | Benzo[a]pyrene Toxicological Summary for Benzo(a)pyrene (PDF) Information Sheet: Benzo(a)pyrene and Groundwater (PDF)
|
HBV20 | Acute | ND | -- |
| Short-term | 0.5 | Developmental; Nervous system | |||
| Subchronic | 0.5* | Developmental; Nervous system | |||
| Chronic | 0.5* | Developmental; Nervous system | |||
| Cancer | 0.1 | Cancer | |||
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| 65-85-0 | Benzoic acid | HRL93 | Chronic | 30,000 | None |
| 119-61-9 | Benzophenone |
HBV20 | Acute | ND | -- |
| Short-term | 900 | Developmental | |||
| Subchronic | 100 | Liver System; Kidney System | |||
| Chronic | 100** | Liver System; Kidney System | |||
| Cancer | NA | -- | |||
| 95-14-7 | 1H-Benzotriazole Toxicological Summary for 1H-Benzotriazole (PDF) Information Sheet: 1H-Benzotriazole, Tolyltriazole, 5-Methyl-1H-Benzotriazole and Groundwater (PDF) |
HBV20 | Acute | ND | -- |
| Short-term | 20 | Developmental | |||
| Subchronic | 20* | Developmental | |||
| Chronic | 20* | Developmental | |||
| Cancer | NA | -- | |||
| 29385-43-1 | methyl-1H-Benzotriazole (Tolyltriazole) Toxicological Summary for Tolyltriazole and 5-methyl-1H-Benzotriazole (PDF) Information Sheet: 1H-Benzotriazole, Tolyltriazole, 5-Methyl-1H-Benzotriazole and Groundwater (PDF)
|
RAA19 | Acute | ND | -- |
| Short-term | 20 | Developmental | |||
| Subchronic | 20* | Developmental | |||
| Chronic | 20* | Developmental | |||
| Cancer | NA | -- | |||
| 136-85-6 | 5-methyl-1H-Benzotriazole Toxicological Summary for Tolyltriazole and 5-methyl-1H-Benzotriazole (PDF) Information Sheet: 1H-Benzotriazole, Tolytriazole, 5-Methyl-1H-Benzotriazole and Groundwater (PDF) |
RAA19 | Acute | ND | -- |
| Short-term | 20 | Developmental | |||
| Subchronic | 20* | Developmental | |||
| Chronic | 20* | Developmental | |||
| Cancer | NA | -- | |||
| 7440-41-7 | Beryllium | HRL93 | Cancer | 0.08 | Cancer |
| 92-52-4 | 1,1'-Biphenyl (Diphenyl) |
HRL93 | Chronic | 300 | Kidney system |
| HBV21 | Acute | 400 | Kidney system | ||
| Short-term | 100 | Kidney system | |||
| Subchronic | 100* | Kidney system | |||
| Chronic | 100* | Kidney system | |||
| Cancer | 10 | Cancer | |||
| 111-44-4 | Bis(chloroethyl) ether (BCEE) | HRL93 | Cancer | 0.3 | Cancer |
| 542-88-1 | Bis(chloromethyl) ether (BCME) | HRL93 | Cancer | 0.002 | Cancer |
| 80-05-7 | Bisphenol A (BPA) |
HRL15 | Acute | ND | -- |
| Short-term | 100 | Developmental; Female reproductive system (E); Liver system; Male reproductive system (E); Kidney system; Thyroid (E) | |||
| Subchronic | 20 | Liver system; Kidney system | |||
| Chronic | 20** | Liver system; Kidney system | |||
| Cancer | NA | -- | |||
| 7440-42-8 | Boron |
RAA17 | Acute | ND | -- |
| Short-term | 500 | Developmental | |||
| Subchronic | 500 | Developmental | |||
| Chronic | 500 | Developmental | |||
| Cancer | NA | -- | |||
| 75-27-4 | Bromodichloromethane Toxicological Summary for Bromodichloromethane (PDF) Information Sheet: Bromodichloromethane and Groundwater (PDF) |
HRL93 | Cancer | 6 | Cancer |
| HBV20 | Acute | 400 | Female reproductive system (E) | ||
| Short-term | 30 | Immune system; Spleen | |||
| Subchronic | 30* | Immune system; Spleen | |||
| Chronic | 30 | Liver system | |||
| Cancer | 3 | Cancer | |||
| 75-25-2 | Bromoform | HRL93 | Cancer | 40 | Cancer |
| 74-83-9 | Bromomethane (Methyl bromide) | HRL93 | Chronic | 10 | Gastrointestinal system |
| 71-36-3 | n-Butanol | HRL93 | Chronic | 700 | Nervous system |
| 85-68-7 | HRL15 | Acute | 100 | Developmental (E) | |
| Short-term | 100 | Developmental (E) | |||
| Subchronic | 100* | Developmental (E) | |||
| Chronic | 100* | Developmental (E) | |||
| Cancer | NA | -- | |||
| 85-70-1 | Butylphthalyl butylglycolate (BPBG) | HRL93 | Chronic | 7,000 | None |
| 7440-43-9 | Cadmium |
HRL15 | Acute | 5 | Developmental |
| Short-term | 1 | Developmental; Nervous system; Renal (kidney) system | |||
| Subchronic | 1 | Developmental; Skeletal | |||
| Chronic | 0.5 | Renal (kidney) system; Skeletal | |||
| Cancer | NA | -- | |||
| 298-46-4 | Carbamazepine |
HRL13 | Acute | 40 | Developmental; Nervous system |
| Short-term | 40 | Developmental; Blood system; Liver system; Immune system; Nervous system; Male reproductive system (E); Female reproductive system (E); Thyroid (E) |
|||
| Subchronic | 40* | Developmental; Blood system; Liver system; Immune system; Nervous system; Male reproductive system (E); Female reproductive system (E);Thyroid (E) | |||
| Chronic | 40* | Developmental; Blood system; Liver system; Immune system; Nervous system; Male reproductive system (E); Female reproductive system (E); Thyroid (E) | |||
| Cancer | NA | -- | |||
| 75-15-0 | Carbon disulfide | HRL93 | Chronic | 700 | Developmental |
| 56-23-5 | Carbon tetrachloride |
HRL13 | Acute | 100 | Developmental; Liver system |
| Short-term | 3 | Liver system | |||
| Subchronic | 3* | Liver system | |||
| Chronic | 3* | Liver system | |||
| Cancer | 1 | Cancer | |||
| 133-90-4 | Chloramben | HRL94 | Chronic | 100 | Liver system |
| 108-90-7 | Chlorobenzene | HRL93 | Chronic | 100 | Liver system |
| 75-00-3 | Chloroethane |
RAA16 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | ND | -- | |||
| Chronic | ND | -- | |||
| Cancer | NA | -- | |||
| 67-66-3 | Chloroform |
HRL18 | Acute | ND | -- |
| Short-term | 20 | Developmental; Liver system; Immune system | |||
| Subchronic | 20* | Developmental; Liver system; Immune system | |||
| Chronic | 20* | Developmental; Liver system; Immune system | |||
| Cancer | NA | -- | |||
| 95-57-8 | 2-Chlorophenol | HRL93 | Chronic | 30 | Developmental |
| 1897-45-6 | Chlorothalonil | HRL94 | Cancer | 30 | Cancer |
| 2921-88-2 | Chlorpyrifos |
HBV13 | Acute | 2 | Nervous system |
| Short-term | 0.6 | Nervous system | |||
| Subchronic | 0.6* | Nervous system | |||
| Chronic | 0.6* | Nervous system | |||
| Cancer | NA | -- | |||
| 5598-15-2 | Chlorpyrifos Oxon (degradate of Chlorpyrifos) |
RAA13 | Acute | 0.9 | Nervous system |
| Short-term | 0.4 | Nervous system | |||
| Subchronic | 0.4* | Nervous system | |||
| Chronic | 0.4* | Nervous system | |||
| Cancer | NA | -- | |||
| 16065-83-1 | Chromium III | HRL94 | Chronic | 20,000 | None |
| 18540-29-9 | Chromium VI | HRL93 | Chronic | 100 | None |
| 210880-92-5; 205510-53-8 | Clothianidin |
HRL18 | Acute | ND | -- |
| Short-term | 200 | Developmental | |||
| Subchronic | 200* | Developmental | |||
| Chronic | 200* | Developmental | |||
| Cancer | NA | -- | |||
| 98-82-8 | Cumene (Isopropyl benzene) | HRL93 | Chronic | 300 | None |
| 21725-46-2 | Cyanazine Toxicological Summary for Cyanazine (PDF) See also degradates Cyanazine acid, Cyanazine amide, Deethylcyanazine, Deethylcyanazine acid, Deethylcyanazine amide, Deethyldeisopropylatrazine, and Deisopropylatrazine as described in the Toxicological Summary for Cyanazine and Atrazine Chlorinated Degradates (PDF). |
HRL18 | Acute | 3 | Developmental; Female reproductive system |
| Short-term | 3 | Developmental; Female reproductive system | |||
| Subchronic | 3 | Developmental; Female reproductive system; Liver system; Kidney system | |||
| Chronic | 1 | None | |||
| Cancer | NA | -- | |||
| 36576-43-9; 36576-42-8 |
Cyanazine acid (CAC) and Cyanazine amide (CAM) (degradates of Cyanazine) Toxicological Summary for Cyanazine and Atrazine Chlorinated Degradates (PDF) |
RAA20 | Acute | 3 | Developmental; Female reproductive system |
| Short-term | 3 | Developmental; Female reproductive system | |||
| Subchronic | 3 | Developmental; Female reproductive system; Liver system; Kidney system | |||
| Chronic | 1 | None | |||
| Cancer | NA | -- | |||
| 57-12-5 | Cyanide, free | HRL93 | Chronic | 100 | Nervous system; Thyroid (E) |
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| 6190-65-4 | Deethylatrazine (DEA) (degradate of Atrazine) Toxicological Summary for Cyanazine and Atrazine Chlorinated Degradates (PDF) |
RAA20 | Chronic | 3 | None |
21725-40-6; |
Deethylcyanazine (DEC), Deethylcyanazine acid (DCAC), and Deethylcyanazine amide (DCAM) (degradates of Cyanazine) Toxicological Summary for Cyanazine and Atrazine Chlorinated Degradates (PDF)
|
RAA20 | Acute | 3 | Developmental; Female reproductive system |
| Short-term | 3 | Developmental; Female reproductive system | |||
| Subchronic | 3 | Developmental; Female reproductive system; Liver system; Kidney system | |||
| Chronic | 1 | None | |||
| Cancer | NA | -- | |||
| 3397-62-4; 1007-28-9 |
Deethyldeisopropylatrazine (DACT, DEDI, DDA) and Deisopropylatrazine (DIA) (degradates of Atrazine and Cyanazine) Toxicological Summary for Cyanazine and Atrazine Chlorinated Degradates (PDF) |
RAA20 | Use Cyanazine HRL values if Cyanazine, CAC, CAM, DEC, DCAC or DCAM are present. Use Atrazine HRL value if Cyanazine, CAC, CAM, DEC, DCAC or DCAM are not present. | ||
| 93413-62-8; 386750-22-7; 300827-87-6; 93414-04-1 | Desvenlafaxine Toxicological Summary for Desvenlafaxine (PDF) Information Sheet: Venlafaxine and Desvenlafaxine and Drinking Water (PDF) |
HBV15 | Acute | ND | -- |
| Short-term | 20 | Developmental; Gastrointestinal system; Male reproductive system; Nervous system (E) | |||
| Subchronic | 20* | Developmental; Gastrointestinal system; Male reproductive system; Nervous system (E) | |||
| Chronic | 20* | Developmental; Gastrointestinal system; Male reproductive system; Nervous system (E) | |||
| Cancer | NA | -- | |||
| 124-48-1 | Dibromochloromethane | HRL93 | Chronic | 10 | Liver system |
| 106-93-4 | 1,2-Dibromoethane (ethylene dibromide, EDB) | HRL93 | Cancer | 0.004 | Cancer |
| 84-74-2 | HRL15 | Acute | 20 | Developmental (E) | |
| Short-term | 20 | Developmental (E) | |||
| Subchronic | 20* | Developmental (E) | |||
| Chronic | 20* | Developmental (E) | |||
| Cancer | NA | -- | |||
| 1918-00-9 | Dicamba | HRL93*** | Chronic | 200 | Developmental |
| 95-50-1 | 1,2-Dichlorobenzene | HRL93 | Chronic | 600 | Liver system |
| 106-46-7 | 1,4-Dichlorobenzene (para) | HRL94*** | Cancer | 10 | Cancer |
1,4-Dichlorobenzene Toxicological Summary for 1,4-Dichlorobenzene (PDF) Information Sheet: 1,4-Dichlorobenzene and Groundwater (PDF) |
HBV20 | Acute | ND | -- | |
| Short-term | 50 | Developmental; Liver system; Nervous system | |||
| Subchronic | 50* | Developmental; Liver system; Nervous system | |||
| Chronic | 50* | Developmental; Liver system; Nervous system | |||
| Cancer | NA | -- | |||
| 91-94-1 | 3,3'-Dichlorobenzidine | HRL93 | Cancer | 0.8 | Cancer |
| 75-71-8 | Dichlorodifluoromethane |
HRL11*** | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | ND | -- | |||
| Chronic | 700 | None | |||
| Cancer | NA | -- | |||
Dichlorodifluoromethane Toxicological Summary for Dichlorodifluoromethane (PDF) Information Sheet: Dichlorodifluoromethane and Drinking Water (PDF) |
RAA17 | Acute | ND | -- | |
| Short-term | ND | -- | |||
| Subchronic | ND | -- | |||
| Chronic | 500 | None | |||
| Cancer | NA | -- | |||
| 72-54-8 | p,p'-Dichlorodiphenyldichloroethane (DDD) | HRL93 | Cancer | 1 | Cancer |
| 72-55-9 | p,p'-Dichlorodiphenyldichloroethylene (DDE) | HRL93 | Cancer | 1 | Cancer |
| 50-29-3 | p,p'-Dichlorodiphenyltrichloroethane (DDT) | HRL93 | Cancer | 1 | Cancer |
| 75-34-3 | RAA16 | Acute | ND | -- | |
| Short-term | 400 | Nervous system | |||
| Subchronic | 400* | Nervous system | |||
| Chronic | 80 | Nervous system | |||
| Cancer | NA | -- | |||
| 107-06-2 | 1,2-Dichloroethane |
HRL13 | Acute | ND | -- |
| Short-term | 200 | Liver system | |||
| Subchronic | 200* | Liver system | |||
| Chronic | 60 | Kidney system; Liver system | |||
| Cancer | 1 | Cancer | |||
| 156-59-2 | cis-1,2-Dichloroethene Toxicological Summary for cis-1,2-Dichloroethene (PDF) Information sheet: cis-1,2-Dichloroethene and Drinking Water (PDF) |
HRL18 | Acute | ND | -- |
| Short-term | 20 | Liver system | |||
| Subchronic | 10 | Kidney system | |||
| Chronic | 6 | Kidney system | |||
| Cancer | NA | -- | |||
| 156-60-5 | trans-1,2-Dichloroethene |
HRL13 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 200 | Immune system | |||
| Chronic | 40 | Immune system | |||
| Cancer | NA | -- | trans-1,2-Dichloroethene Toxicological Summary for trans-1,2-Dichloroethene (HBV 2020) (PDF) |
HBV20 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 50 | Immune system | |||
| Chronic | 9 | Immune system | |||
| Cancer | NA | -- | |||
| 75-35-4 | 1,1-Dichloroethylene (Vinylidene chloride) Toxicological Summary for 1,1-Dichloroethylene (Vinylidene chloride) (PDF) |
HRL11*** | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 200 | Liver system | |||
| Chronic | 200 | Liver system | |||
| Cancer | NA | -- | |||
1,1-Dichloroethylene (Vinylidene chloride) Toxicological Summary for 1,1-Dichloroethylene (Vinylidene chloride) (2020) (PDF) Information Sheet: 1,1-Dichloroethylene and Groundwater (PDF) |
HBV20 | Acute | ND | -- | |
| Short-term | ND | -- | |||
| Subchronic | 200 | Liver system | |||
| Chronic | 200 | Liver system | |||
| Cancer | NA | -- | |||
| 75-43-4 | Dichlorofluoromethane (DCFM) Toxicological Summary for Dichlorofluoromethane (PDF) Information sheet: Dichlorofluoromethane and Drinking Water (PDF) |
RAA17 | Acute | ND | -- |
| Short-term | 20 | Developmental; Liver system; Immune system | |||
| Subchronic | 20* | Developmental; Liver system; Immune system; | |||
| Chronic | 20* | Developmental; Liver system; Immune system; | |||
| Cancer | NA | -- | |||
| 75-09-2 | Dichloromethane (Methylene chloride) | HRLMCL | Chronic | 5 | see USEPA Organic Chemicals table |
| 120-83-2 | 2,4-Dichlorophenol | HRL93 | Chronic | 20 | Immune system |
| 94-75-7 | 2,4-Dichlorophenoxyacetic acid (2,4-D) Toxicological Summary for 2,4-Dichlorophenoxyacetic acid (PDF) |
HRL18 | Acute | ND | -- |
| Short-term | 30 | Adrenal; Developmental; Thyroid (E) | |||
| Subchronic | 30* | Adrenal; Developmental; Thyroid (E) | |||
| Chronic | 30* | Adrenal; Developmental; Thyroid (E) | |||
| Cancer | ND | -- | |||
| 78-87-5 | 1,2-Dichloropropane Toxiocological Summary for 1,2-Dichloropropane (HBV 2021) (PDF) |
HRL94 | Cancer | 5 | Cancer |
| HBV21 | Acute | ND | -- | ||
| Short-term | 20 | Developmental | |||
| Subchronic | 20* | Developmental | |||
| Chronic | 20* | Developmental | |||
| Cancer | 3 | Cancer | |||
| 542-75-6 | 1,3-Dichloropropene | HRL94 | Cancer | 2 | Cancer |
| 60-57-1 | Dieldrin |
HRL18 | Acute | ND | -- |
| Short-term | 0.2 | Developmental; Immune system; Nervous system | |||
| Subchronic | 0.2* | Developmental; Immune system; Nervous system | |||
| Chronic | 0.2 | Developmental; Liver system; Immune system; Nervous system | |||
| Cancer | 0.006 | Cancer | |||
| 134-62-3 | N,N-Diethyl-meta-toluamide (DEET) Toxicological Summary for N,N-Diethyl-meta-toluamide (DEET) (PDF) |
HRL13 | Acute | ND | -- |
| Short-term | 200 | Developmental; Nervous system | |||
| Subchronic | 200* | Developmental; Nervous system | |||
| Chronic | 200* | Developmental; Nervous system | |||
| Cancer | NA | -- | |||
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| 117-81-7 | Di(2-ethylhexyl)phthalate (DEHP) |
HRL15 | Acute | 20 | Developmental (E); Male reproductive system (E) |
| Short-term | 20 | Developmental (E); Male reproductive system (E) | |||
| Subchronic | 20* | Developmental (E); Male reproductive system (E) | |||
| Chronic | 20* | Developmental (E); Male reproductive system (E) | |||
| Cancer | 7 | Cancer | |||
| 84-66-2 | Diethyl phthalate | HRL93 | Chronic | 6,000 | None |
| 87674-68-8 163515-14-8 |
Toxicological Summary for Dimethenamid & Dimethenamid-P (PDF) Information Sheet: Dimethenamid and Drinking Water (PDF) See also degradates: Dimethenamid ESA & Dimethenamid OXA (PDF) |
HRL15 |
Acute | ND | -- |
| Short-term | 600 | Developmental; Liver system; Nervous system; Female reproductive system | |||
| Subchronic | 600* | Developmental; Liver system; Nervous system; Female reproductive system | |||
| Chronic | 300 | Liver system | |||
| Cancer | NA | -- | |||
| 205939-58-8, 380412-59-9 | Dimethenamid ESA Toxicological Summary for Dimethenamid Degradates: ESA and OXA (PDF) |
RAA13 |
Acute | ND | -- |
| Short-term | 600 | Developmental; Liver system; Nervous system; Female reproductive system | |||
| Subchronic | 600 | Developmental; Liver system; Nervous system; Female reproductive system | |||
| Chronic | 300 | Liver system | |||
| Cancer | NA | -- | |||
| 105-67-9 | 2,4-Dimethylphenol | HRL93 | Chronic | 100 | Blood system; Nervous system |
| 131-11-3 | Dimethylphthalate | HRL94 | Chronic | 70,000 | Kidney system |
| 51-28-5 | 2,4-Dinitrophenol | HRL94 | Chronic | 10 | Eyes |
| 88-85-7 | Dinoseb |
HRL18 | Acute | ND | -- |
| Short-term | 8 | Developmental | |||
| Subchronic | 8* | Developmental | |||
| Chronic | 8* | Developmental | |||
| Cancer | NA | -- | |||
| 123-91-1 | 1,4-Dioxane |
HRL13 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 300 | Liver system; Kidney system; Respiratory system | |||
| Chronic | 100 | Liver system; Kidney system; Respiratory system | |||
| Cancer | 1 | Cancer | |||
| 298-04-4 | Disulfoton | HRL94 | Chronic | 0.3 | Nervous system |
| 57-63-6 | 17α-Ethinylestradiol Toxicological Summary for 17α-Ethinylestradiol (PDF) Information Sheet: 17α-Ethinylestradiol and Mestranol and Drinking Water (PDF) |
HBV20 | Acute | ND | -- |
| Short-term | 0.0005 | Developmental (E); Female Reproductive system (E); Male Reproductive system (E) | |||
| Subchronic | 0.0002 | Developmental | |||
| Chronic | 0.0002 | Developmental | |||
| Cancer | ND | -- | |||
| 100-41-4 | Ethylbenzene |
HRL11*** | Acute | ND | -- |
| Short-term | 50 | Liver system; Kidney system | |||
| Subchronic | 50* | Liver system; Kidney system | |||
| Chronic | 50* | Liver system; Kidney system | |||
| Cancer | NA | -- | |||
Ethylbenzene |
HBV20 | Acute | ND | -- | |
| Short-term | 40 | Liver system; Kidney system | |||
| Subchronic | 40* | Liver system; Kidney system | |||
| Chronic | 40* | Liver system; Kidney system | |||
| Cancer | NA | -- | |||
| 759-94-4 | S-Ethyl-N,N-dipropylthiocarbamate (EPTC) Toxicological Summary for S-Ethyl-N,N-dipropylthiocarbamate (PDF) Information Sheet: S-Ethyl-N,N-dipropylthiocarbamate (EPTC) and Drinking Water (PDF) |
HRL18 | Acute | 300 | Nervous system |
| Short-term | 300 | Developmental; Female reproductive system; Nervous system | |||
| Subchronic | 90 | Cardiovascular system | |||
| Chronic | 40 | Cardiovascular system | |||
| Cancer | NA | -- | |||
| 60-29-7 | Ethyl ether |
RAA16 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 1000 | Liver system; Kidney system | |||
| Chronic | 200 | Liver system; Kidney system | |||
| Cancer | NA | -- | |||
| 107-21-1 | Ethylene glycol |
HRL11*** | Acute | 4,000 | Developmental |
| Short-term | 4,000 | Developmental | |||
| Subchronic | 2,000 | Developmental; Kidney system | |||
| Chronic | 2,000 | Developmental; Kidney system | |||
| Cancer | NA | -- | |||
Ethylene glycol |
HBV20 | Acute | ND | -- | |
| Short-term | 2,000 | Developmental | |||
| Subchronic | 2,000 | Developmental; Kidney system | |||
| Chronic | 2,000 | Developmental; Male reproductive system; Kidney system | |||
| Cancer | NA | -- | |||
| 206-44-0 | Fluoranthene |
HRL18 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 200 | Liver system; Kidney system | |||
| Chronic | 70 | Liver system; Kidney system | |||
| Cancer | NA | see Guidance for Evaluating the Cancer Potency of PAH Mixtures (PDF) | |||
| 86-73-7 | Fluorene (9H-Fluorene) |
HRL93*** | Chronic | 300 | Blood system |
| HBV20 | Acute | ND | -- | ||
| Short-term | ND | -- | |||
| Subchronic | 200 | Blood system, Spleen | |||
| Chronic | 80 | Blood system, Spleen | |||
| Cancer | NA | -- | |||
| 72178-02-0 | Fomesafen Toxicological Summary for Fomesafen (PDF)
|
HBV20 | Acute | ND | -- |
| Short-term | 200 | Developmental, Hepatic (liver) system, Immune system | |||
| Subchronic | 200* | Developmental, Hepatic (liver) system, Immune system | |||
| Chronic | 20 | Hepatic (liver) system | |||
| Cancer | NA | -- | |||
| 50-00-0 | Formaldehyde | HRL94 | Chronic | 1,000 | Gastrointestinal system |
| 1071-83-6; 38641-94-0; 40465-76-7; 34494-04-7; 114370-14-8; 39600-42-5 | Glyphosate |
HBV17 | Acute | ND | -- |
| Short-term | 1,000 | Developmental | |||
| Subchronic | 1,000 | Gastrointestinal system | |||
| Chronic | 500 | Gastrointestinal system | |||
| Cancer | NA | -- | |||
| 76-44-8 | Heptachlor | HRL93 | Cancer | 0.08 | Cancer |
| 1024-57-3 | Heptachlor epoxide | HRL93 | Cancer | 0.04 | Cancer |
| 118-74-1 | Hexachlorobenzene | HRL93 | Cancer | 0.2 | Cancer |
| 87-68-3 | Hexachlorobutadiene | HRL93 | Chronic | 1 | Kidney system |
| 110-54-3 | Hexane (n-hexane) | HRL94 | Chronic | 400 | Nervous system |
| 138261-41-3 | Imidacloprid |
HBV20 | Acute | 100 | Nervous system |
| Short-term | 2 | Immune system | |||
| Subchronic | 2* | Immune system | |||
| Chronic | 2* | Immune system | |||
| Cancer | NA | -- | |||
| 78-83-1 | Isobutanol |
HBV16 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 700 | Male reproductive system | |||
| Chronic | 300 | Male reproductive system | |||
| Cancer | NA | -- | |||
| 78-59-1 | Isophorone | HRL93 | Chronic | 100 | Kidney system |
| 330-55-2 | Linuron | HRL93 | Chronic | 1 | Blood system |
| 7439-96-5 | Manganese |
HRL93*** | Chronic | 100 | Nervous system |
| HBV20 | Acute | ND | -- | ||
| Short-term | 100 | Developmental; Nervous system | |||
| Subchronic | ND | -- | |||
| Chronic | ND | -- | |||
| Cancer | NA | -- | |||
| 72-33-3 | Mestranol Toxicological Summary for Mestranol (PDF) Information Sheet: 17α-Ethinylestradiol and Mestranol and Drinking Water (PDF) |
RAA16 | Acute | ND | -- |
| Short-term | 0.0007 | Developmental (E); Female Reproductive system (E); Male Reproductive system (E) | |||
| Subchronic | 0.0002 | Developmental | |||
| Chronic | 0.0002** | Developmental | |||
| Cancer | ND | -- | |||
| 67-56-1 | Methanol | HRL94 | Chronic | 3,000 | Liver system; Nervous system |
| 94-74-6 | 2-Methyl-4-chlorophenoxyacetic acid (MCPA) | HRL93 | Chronic | 3 | Liver system; Kidney system |
| 78-93-3 | Methyl ethyl ketone (MEK, 2-butanone) | HRL94 | Chronic | 4,000 | Developmental |
| 108-10-1 | Methyl isobutyl ketone (MIBK) | HRL94 | Chronic | 300 | Liver system; Kidney system |
| 1634-04-4 | Methyl tert-butyl ether (MTBE) Toxicological Summary for Methyl tert-butyl ether (MTBE) (PDF) Information Sheet for Methyl tert-butyl ether (MTBE) and Drinking Water (PDF) |
RAA13 | Acute | ND | -- |
| Short-term | 700 | Liver system; Nervous system; Kidney system | |||
| Subchronic | 700* | Liver system; Nervous system; Kidney system | |||
| Chronic | 700* | Liver system; Nervous system; Kidney system | |||
| Cancer | 60 | Cancer | |||
| 91-57-6 | 2-Methylnaphthalene Toxicological Summary for 2-Methylnaphthalene (PDF) Information Sheet: 2-Methylnaphthalene and Drinking Water (PDF) |
RAA13 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | ND | -- | |||
| Chronic | 8 | Respiratory system | |||
| Cancer | ND | -- | |||
| 95-48-7 | 2-Methylphenol (o-cresol) | HRL93 | Chronic | 30 | Nervous system |
| 108-39-4 | 3-Methylphenol (m-cresol) | HRL93 | Chronic | 30 | Nervous system |
| 106-44-5 | 4-Methylphenol (p-cresol) | HRL94 | Chronic | 3 | None |
| 51218-45-2; 87392-12-9 |
Metolachlor and s-Metolachlor Toxicological Summary for Metolachlor and s-Metolachlor (HRL 2011) (PDF) |
HRL11*** | Acute | 400 | Developmental |
| Short-term | 400 | Developmental | |||
| Subchronic | 300 | None | |||
| Chronic | 300** | None | |||
| Cancer | NA | -- | |||
Metolachlor and s-Metolachlor
Toxicological Summary for Metolachlor and s-Metolachlor (HBV 2020) (PDF) |
HBV20 | Acute | ND | -- | |
| Short-term | 300 | Developmental | |||
| Subchronic | 300* | Developmental | |||
| Chronic | 300* | Developmental | |||
| Cancer | NA | -- | |||
| 171118-09-5 | Metolachlor ESA Toxicological Summary for Metolachlor ESA (HRL 2011) (PDF) |
HRL11*** | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 4,000 | Liver system | |||
| Chronic | 800 | Liver system | |||
| Cancer | NA | -- | |||
Metolachlor ESA (degradate of Metolachlor) Toxicological Summary for Metolachlor ESA (HBV 2020) (PDF) Information Sheet: Metolachlor ESA/OXA and Drinking Water (PDF) |
HBV20 | Acute | ND | -- | |
| Short-term | ND | -- | |||
| Subchronic | 7,000 | Liver system | |||
| Chronic | 1,000 | Liver system | |||
| Cancer | NA | -- | |||
| 152019-73-3 | Metolachlor OXA Toxicological Summary for Metolachlor OXA (HRL 2011) (PDF) |
HRL11*** | Acute | ND | -- |
| Short-term | 3,000 | None | |||
| Subchronic | 3,000* | None | |||
| Chronic | 800 | None | |||
| Cancer | NA | -- | |||
Metolachlor OXA (degradate of Metolachlor) Toxicological Summary for Metolachlor OXA (HBV 2020) (PDF) Information Sheet: Metolachlor ESA/OXA and Drinking Water (PDF) |
HBV20 | Acute | ND | -- | |
| Short-term | 5,000 | None | |||
| Subchronic | 5,000* | None | |||
| Chronic | 1,000 | None | |||
| Cancer | NA | -- | |||
| 21087-64-9 | Metribuzin Toxicological Summary for Metribuzin (PDF) See also degradates: Metribuzin DA, DK, and DADK (PDF) |
HRL13 | Acute | 30 | Developmental; Nervous system |
| Short-term | 10 | Thyroid (E) | |||
| Subchronic | 10* | Thyroid (E) | |||
| Chronic | 10* | Thyroid (E) | |||
| Cancer | NA | -- | |||
| 35045-02-4; 56507-37-0; 52236-30-3 |
Metribuzin DA, DK, and DADK Toxicological Summary for Metribuzin Degradates DA, DK, and DADK (PDF) Information Sheet: Metribuzin Degradates in Drinking Water (PDF) |
RAA12 | Acute | 30 | Developmental; Nervous system |
| Short-term | 10 | Thyroid (E) | |||
| Subchronic | 10* | Thyroid (E) | |||
| Chronic | 10* | Thyroid (E) | |||
| Cancer | NA | -- | |||
101043-37-2 |
HBV15 | Acute | NA | -- | |
| Short-term | 0.1 | Liver System | |||
| Subchronic | 0.1* | Liver System | |||
| Chronic | 0.1 | Liver System | |||
| Cancer | NA | -- | |||
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|||||
| 91-20-3 | Naphthalene |
HRL13 | Acute | 70 | Nervous system |
| Short-term | 70 | Nervous system | |||
| Subchronic | 70* | Nervous system | |||
| Chronic | 70 | Nervous system; Spleen | |||
| Cancer | NA | -- | |||
| 7440-02-0 | Nickel, soluble salts | HRL93 | Chronic | 100 | None |
| 14797-55-8 | Nitrate (as nitrogen) | HRLMCL | Acute | 10,000 | see USEPA Inorganic Chemicals table |
| 62-75-9 | N-Nitrosodimethylamine (NDMA) Toxicological Summary for N-Nitrosodimethylamine (NDMA) (PDF) |
HBV17 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | ND | -- | |||
| Chronic | ND | -- | |||
| Cancer | 0.005 | Cancer | |||
| 86-30-6 | N-Nitrosodiphenylamine | HRL93 | Cancer | 70 | Cancer |
| 84852-15-3 | Nonylphenol Toxicological Summary for p-Nonylphenol, branched isomers (PDF) |
HBV20 | Acute | ND | -- |
| Short-term | 100 | Developmental; Female reproductive system | |||
| Subchronic | 40 | Kidney system | |||
| Chronic | 20 | Kidney system | |||
| Cancer | NA | -- | |||
| 140-66-9 | 4-tert-Octylphenol |
HBV20 | Acute | ND | -- |
| Short-term | 100 | Developmental | |||
| Subchronic | 100* | Developmental | |||
| Chronic | 100* | Developmental | |||
| Cancer | NA | -- | |||
| 87-86-5 | Pentachlorophenol (PCP) Information Sheet: Pentachlorophenol and Drinking Water (PDF) |
HRL15 | Acute | 7 | Developmental; Thyroid (E) |
| Short-term | 7 | Developmental (E); Thyroid (E) | |||
| Subchronic | 7* | Developmental (E); Liver system; Immune system; Male Reproductive system; Thyroid (E) | |||
| Chronic | 7* | Developmental (E); Liver system; Immune system; Male Reproductive system; Thyroid (E) | |||
| Cancer | 0.3 | Cancer | |||
| 45187-15-3; 375-73-5 |
Perfluorobutane sulfonate (PFBS) Toxicological Summary for Perfluorobutane sulfonate (PFBS) (HRL 2011) (PDF) |
HRL11*** | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 9 | Blood system; Liver system; Kidney system | |||
| Chronic | 7 | Blood system; Liver system; Kidney system | |||
| Cancer | NA | -- | |||
Perfluorobutane sulfonate (PFBS) Toxicological Summary for Perfluorobutane sulfonate (PFBS) (HBV 2020) (PDF) |
HBV20 | Acute | ND | -- | |
| Short-term | 3 | Developmental; Female reproductive system (E); Thyroid (E) | |||
| Subchronic | 3* | Developmental; Female reproductive system (E); Thyroid (E) | |||
| Chronic | 2 | Kidney system | |||
| Cancer | NA | -- | |||
| 45048-62-2; 375-22-4 |
|
HRL18 | Acute | ND | -- |
| Short-term | 7 | Liver system; Thyroid (E) | |||
| Subchronic | 7* | Liver system; Thyroid (E) | |||
| Chronic | 7* | Liver system; Thyroid (E) | |||
| Cancer | NA | -- | |||
| 108427-53-8; 355-46-4; 3871-99-6 |
Perfluorohexane sulfonate (PFHxS) Toxicological Summary for Perfluorohexane sulfonate (PFHxS) (PDF) |
HBV20 | Acute | ND | -- |
| Short-term | 0.047 | Liver system; Thyroid (E) | |||
| Subchronic | 0.047 | Liver system; Thyroid (E) | |||
| Chronic | 0.047 | Liver system; Thyroid (E) | |||
| Cancer | NA | -- | |||
| 45285-51-6; 335-67-1; 335-66-0; 3825-26-1; 2395-00-8; 335-93-3; 335-95-5 |
Perfluorooctanoate (PFOA) Toxicological Summary for Perfluorooctanoate (PFOA) (PDF) |
HRL18 | Acute | NA | -- |
| Short-term | 0.035 | Developmental; Liver system; Immune system; Kidney system | |||
| Subchronic | 0.035 | Developmental; Liver system; Immune system; Kidney system | |||
| Chronic | 0.035 | Developmental; Liver system; Immune system; Kidney system | |||
| Cancer | NA | -- | |||
| 45298-90-6; 1763-23-1; 29081-56-9; 70225-14-8; 2795-39-3; 29457-72-5 |
Perfluorooctane Sulfonate (PFOS) and Salts Toxicological Summary for Perfluorooctane Sulfonate (PFOS) and Salts (PDF) |
HRL09*** | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | ND | -- | |||
| Chronic | 0.3 | Developmental; Liver system; Thyroid (E) | |||
| Cancer | NA | -- | |||
Perfluorooctane Sulfonate (PFOS) Toxicological Summary for Perfluorooctane Sulfonate (PFOS) (2020) (PDF) |
HBV20 | Acute | NA | -- | |
| Short-term | 0.015 | Adrenal (E); Developmental; Liver system; Immune system; Thyroid (E) | |||
| Subchronic | 0.015 | Adrenal (E); Developmental; Liver system; Immune system; Thyroid (E) | |||
| Chronic | 0.015 | Adrenal (E); Developmental; Liver system; Immune system; Thyroid (E) | |||
| Cancer | NA | -- | |||
| 108-95-2 | Phenol | HRL93 | Chronic | 4,000 | Developmental |
| 1918-02-1 | Picloram | HRL93 | Chronic | 500 | Liver system |
| 1336-36-3 | Polychlorinated biphenyls (PCBs) | HRL94 | Cancer | 0.04 | Cancer |
| 1610-18-0 | Prometon | HRL93 | Chronic | 100 | None |
| 1918-16-7 | Propachlor | HRL93 | Chronic | 90 | None |
| 175013-18-0 | Pyraclostrobin |
HBV16 | Acute | 300 | Developmental; Female Reproductive system |
| Short-term | 100 | Developmental; Female Reproductive system; Gastrointestinal system; Spleen | |||
| Subchronic | 100 | Developmental; Female Reproductive system; Gastrointestinal system; Blood system; Liver system; Immune system; Spleen | |||
| Chronic | 100** | Developmental; Female Reproductive system; Gastrointestinal system; Blood system; Liver system; Immune system; Spleen | |||
| Cancer | NA | -- | |||
| 129-00-0 | Pyrene |
HRL18 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 90 | Kidney system | |||
| Chronic | 50 | Kidney system | |||
| Cancer | NA | -- | |||
| 91-22-5 | Quinoline |
HBV20 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | ND | -- | |||
| Chronic | 4 | Blood system; Liver system; Kidney system; Respiratory system; Spleen | |||
| Cancer | 0.03 | Cancer | |||
| 7782-49-2 | Selenium | HRL93 | Chronic | 30 | None |
| 7440-22-4 | Silver | HRL93 | Chronic | 30 | None |
| 122-34-9 | Simazine | HRLMCL | Chronic | 4 | see USEPA Organic Chemicals table |
| 7440-24-6 | Strontium |
RAA19 | Acute | ND | -- |
| Short-term | 3000 | Developmental; Skeletal | |||
| Subchronic | 3000* | Developmental; Skeletal | |||
| Chronic | 3000* | Developmental; Skeletal | |||
| Cancer | NA | -- | |||
| 57-68-1 | Sulfamethazine Toxicological Summary for Sulfamethazine (PDF) Information Sheet: Sulfonamide Antibiotics and Drinking Water (PDF) |
HRL15 | Acute | ND | -- |
| Short-term | 100 | Thyroid | |||
| Subchronic | 100* | Thyroid | |||
| Chronic | 100* | Thyroid | |||
| Cancer | NA | -- | |||
| 723-46-6 | Sulfamethoxazole Toxicological Summary for Sulfamethoxazole (PDF) Information Sheet: Sulfonamide Antibiotics and Drinking Water (PDF) |
RAA13 | Acute | ND | -- |
| Short-term | 100 | Thyroid | |||
| Subchronic | 100* | Thyroid | |||
| Chronic | 100* | Thyroid | |||
| Cancer | NA | -- | |||
| 630-20-6 | 1,1,1,2-Tetrachloroethane | HRL93 | Chronic | 70 | Kidney system; Liver system |
| 79-34-5 | 1,1,2,2-Tetrachloroethane | HRL94 | Cancer | 2 | Cancer |
| 127-18-4 | Tetrachloroethylene (PERC or PCE) Toxicological Summary for Tetrachloroethylene (PDF) Information Sheet: Tetrachloroethylene (PCE) and Drinking Water (PDF) |
HRLMCL*** | Chronic | 5 | see USEPA Organic Chemicals table |
| HBV14 | Acute | ND | -- | ||
| Short-term | ND | -- | |||
| Subchronic | 7 | Nervous system | |||
| Chronic | 7** | Nervous system | |||
| Cancer | 4 | Cancer | |||
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| 109-99-9 | Tetrahydrofuran |
HRL18 | Acute | ND | -- |
| Short-term | 600 | Developmental | |||
| Subchronic | 600* | Developmental | |||
| Chronic | 600* | Developmental | |||
| Cancer | ND | -- | |||
| 7440-28-0 | Thallium salts | HRL94 | Chronic | 0.6 | Liver system |
| 153719-23-4 | Thiamethoxam |
HRL18 | Acute | ND | -- |
| Short-term | 400 | Developmental; Female reproductive system; Liver system | |||
| Subchronic | 200 | Male reproductive system | |||
| Chronic | 200** | Male reproductive system | |||
| Cancer | NA | -- | |||
| 7440-31-5 | Tin | HRL94 | Chronic | 4,000 | Liver system; Kidney system |
| 108-88-3 | Toluene |
HRL11*** | Acute | ND | -- |
| Short-term | 200 | Immune system; Nervous system | |||
| Subchronic | 200* | Immune system; Nervous system | |||
| Chronic | 200* | Immune system; Nervous system | |||
| Cancer | NA | -- | |||
Toluene |
HBV20 | Acute | ND | -- | |
| Short-term | 70 | Immune system; Nervous system | |||
| Subchronic | 70* | Immune system; Nervous system | |||
| Chronic | 70* | Immune system; Nervous system | |||
| Cancer | NA | -- | |||
| Not available | Total Petroleum Hydrocarbon. See Other Guidance: Chemical Specific | ||||
| 8001-35-2 | Toxaphene | HRL93 | Cancer | 0.3 | Cancer |
| 120-82-1 | 1,2,4-Trichlorobenzene |
HRL13 | Acute | ND | -- |
| Short-term | 100 | Liver system; Adrenal (E); Blood system | |||
| Subchronic | 100* | Liver system; Adrenal (E); Blood system | |||
| Chronic | 100 | Liver system; Adrenal (E); Kidney system | |||
| Cancer | 4 | Cancer | |||
| 108-70-3 | 1,3,5-Trichlorobenzene |
RAA12 | Acute | ND | -- |
| Short-term | 100 | Liver system; Adrenal (E); Blood System | |||
| Subchronic | 100* | Liver system; Adrenal (E); Blood system | |||
| Chronic | 100 | Liver system; Adrenal (E); Kidney system | |||
| Cancer | 4 | Cancer | |||
| 71-55-6 | 1,1,1-Trichloroethane Toxicological Summary for 1,1,1-Trichloroethane (PDF) Information Sheet: 1,1,1-Trichloroethane and Drinking Water (PDF) |
HRL18 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 9,000 | Liver system; Male reproductive system | |||
| Chronic | 5,000 | Liver system; Male reproductive system | |||
| Cancer | NA | -- | |||
| 79-00-5 | 1,1,2-Trichloroethane | HRL93 | Chronic | 3 | Immune system |
| 79-01-6 | 1,1,2-Trichloroethylene (TCE) Toxicological Summary for 1,1,2-Trichloroethylene (TCE) (PDF) |
HRL15 | Acute | ND | -- |
| Short-term | 0.4 | Developmental; Immune | |||
| Subchronic | 0.4 | Developmental; Immune | |||
| Chronic | 0.4** | Developmental; Immune | |||
| Cancer | 2 | Cancer | |||
| 75-69-4 | Trichlorofluoromethane | HRL93 | Chronic | 2,000 | None |
| 88-06-2 | 2,4,6-Trichlorophenol | HRL93 | Cancer | 30 | Cancer |
| 93-76-5 | 2,4,5-Trichlorophenoxyacetic acid | HRL93 | Chronic | 70 | Developmental; Blood system |
| 93-72-1 | 2-(2,4,5-Trichlorophenoxy) propionic acid | HRLMCL | Chronic | 50 | see USEPA Organic Chemicals table |
| 96-18-4 | 1,2,3-Trichloropropane |
HRL13 | Acute | 7 | Developmental |
| Short-term | 7 | Developmental | |||
| Subchronic | 7* | Developmental | |||
| Chronic | 7* | Developmental | |||
| Cancer | 0.003 | Cancer | |||
| 76-13-1 | 1,1,2-Trichloro-1,2,2-trifluoroethane | HRL93 | Chronic | 200,000 | None |
| 101-20-2 | Triclocarban |
RAA13 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | ND | -- | |||
| Chronic | 100 | Blood system; Liver system; Male reproductive system; Kidney system | |||
| Cancer | NA | -- | |||
| 3380-34-5 | Triclosan |
HRL15 | Acute | ND | -- |
| Short-term | 50 | Developmental; Liver system; Thyroid (E); Female Reproductive system (E) | |||
| Subchronic | 50* | Developmental; Liver system; Thyroid (E); Female Reproductive system (E) | |||
| Chronic | 50* | Developmental; Liver system; Thyroid (E); Female Reproductive system (E) | |||
| Cancer | NA | -- | |||
| 526-73-8 | 1,2,3-Trimethylbenzene |
HBV20 | Acute | ND | -- |
| Short-term | 30 | Nervous system | |||
| Subchronic | 30* | Nervous system | |||
| Chronic | 30* | Nervous system | |||
| Cancer | NA | -- | |||
| 95-63-6 | 1,2,4-Trimethylbenzene |
HBV20 | Acute | ND | -- |
| Short-term | 30 | Nervous system | |||
| Subchronic | 30* | Nervous system | |||
| Chronic | 30* | Nervous system | |||
| Cancer | NA | -- | |||
| 108-67-8 | 1,3,5-Trimethylbenzene Toxicological Summary for 1,3,5-Trimethylbenzene (2009) (PDF) |
HRL09*** | Acute | ND | -- |
| Short-term | 100 | Liver system | |||
| Subchronic | 100* | Liver system | |||
| Chronic | 100* | Liver system | |||
| Cancer | NA | -- | |||
1,3,5-Trimethylbenzene |
HBV20 | Acute | ND | -- | |
| Short-term | 30 | Nervous system | |||
| Subchronic | 30* | Nervous system | |||
| Chronic | 30* | Nervous system | |||
| Cancer | NA | -- | |||
| 99-35-4 | 1,3,5-Trinitrobenzene | HRL93 | Chronic | 0.3 | None |
| 78-51-3 | Tris(2-butoxyethyl) phosphate (TBEP) Toxicological Summary for Tris(2-butoxyethyl) phosphate (PDF) |
HBV20 | Acute | ND | -- |
| Short-term | 30 | Hepatic (liver) system | |||
| Subchronic | 30* | Hepatic (liver) system | |||
| Chronic | 30 | Hepatic (liver) system | |||
| Cancer | NA | -- | |||
| 115-96-8 | Tris(2-chloroethyl) phosphate (TCEP) Toxicological Summary for Tris(2-chloroethyl)phosphate (PDF) |
HRL13 | Acute | ND | -- |
| Short-term | 300 | Developmental; Nervous system; Kidney system | |||
| Subchronic | 200 | Kidney system | |||
| Chronic | 200** | Kidney system | |||
| Cancer | 5 | Cancer | |||
| 13674-87-8 | Tris(1,3-dichloroisopropyl)phosphate (TDCPP) Toxicological Summary for Tris(1,3-dichloroisopropyl)phosphate (PDF) |
HBV13 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 20 | Liver system; kidney system | |||
| Chronic | 9 | Kidney system; Male reproductive system | |||
| Cancer | 0.8 | Cancer | |||
| 7440-62-2 | Vanadium | HRL94 | Chronic | 50 | None |
| 93413-69-5; 99300-78-4 | Venlafaxine Toxicological Summary for Venlafaxine (PDF) Information Sheet: Venlafaxine and Desvenlafaxine and Drinking Water (PDF) |
HBV15 | Acute | ND | -- |
| Short-term | 10 | Developmental; Gastrointestinal system; Male reproductive system; Nervous system (E) | |||
| Subchronic | 10* | Developmental; Gastrointestinal system; Male reproductive system; Nervous system (E) | |||
| Chronic | 10* | Developmental; Gastrointestinal system; Male reproductive system; Nervous system (E) | |||
| Cancer | NA | -- | |||
| 75-01-4 | Vinyl Chloride |
HRL18 | Acute | ND | -- |
| Short-term | ND | -- | |||
| Subchronic | 90 | Liver system | |||
| Chronic | 10 | Liver system | |||
| Cancer | 0.2 | Cancer | |||
| 1330-20-7 | Xylenes Toxicological Summary for Xylenes |
HRL11*** | Acute | 800 | Nervous system |
| Short-term | 300 | Nervous system | |||
| Subchronic | 300* | Kidney system; Nervous system | |||
| Chronic | 300* | Kidney system; Nervous system | |||
| Cancer | NA | -- | |||
Xylenes |
HBV20 | Acute | 700 | Nervous system | |
| Short-term | 300 | Developmental, Nervous system | |||
| Subchronic | 300 | Developmental, Nervous system, Kidney system | |||
| Chronic | 300** | Developmental, Nervous system, Kidney system | |||
| Cancer | NA | -- | |||
| 7440-66-6 | Zinc | HRL94 | Chronic | 2,000 | None |
| Go to > top. | |||||
NA - Not Applicable
ND - Not derived due to insufficient information
None - Nonspecific effects that could not be attributed to an organ system
(E) = Endocrine mediated effect on the specified target organ
*Set at short-term value
**Set at subchronic value
***Dual guidance applies: See Dual Guidance for Drinking Water
For more information about this page, please contact the Environmental Health Division: health.risk@state.mn.us
